Diagnostik bei Fieber unklarer Genese (FUO)

Zusammenfassung

Nuklearmedizinische Entzündungsszintigraphien haben sich bei der septischen Entzündungsherdsuche bewährt. Unbefriedigend bleibt aber bislang die Anwendung nuklearmedizinischer sowie radiologischer, sonographischer Verfahren bei Patienten mit Fieber unklarer Genese (FUO). Im Gegensatz zu akut entzündlichen, septischen Prozessen leiden meist ältere Patienten mit FUO öfters an okkulten Tumoren, atypischen Pneumonien, Hämatoblastosen, malignen Lymphomen etc. Neuerdings erlaubt ¹⁸ F(Fluor-18)-Fluordeoxy(i)glukose-PET (¹⁸F-FDG PET) treffsicher das Auffinden okkulter Veränderungen und aktuelle Daten zeigen, dass eine diagnostisch wertvolle Einordnung dieser Veränderungen zu verschiedenen Krankheitsentitäten möglich ist.

Summary

Nuclear medicine imaging is now well accepted for the localization of septic foci. But in patients the results of infection scintigraphy, radiology and ultrasound remain unsatisfactory in the diagnosis of fever of unknown origin (FUO). In contrast to septic infections, patients with FUO – mostly in elderly patients – tend to have such conditions as occult tumours, atypical pneumonia, hematoblastosis, malignant lymphomas. ¹⁸F(Fluor-18)-Fluordeoxyglucose-PET (¹⁸F-FDG PET) has made it possible to localize symptomatically occult changes with a high diagnostic accuracy and to achieve differentiation between benign and malignant changes.

Schlüsselwörter

Fieber unklarer Genese - FUO - Entzündungsszintigraphie - PET

Keywords

Fever of unknown origin - FUO - imaging infection - PET

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