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Semin Thromb Hemost 2009; 35(7): 665-670
DOI: 10.1055/s-0029-1242720
© Thieme Medical Publishers

Particulate Air Pollution and Cardiovascular Risk: Short-term and Long-term Effects

Massimo Franchini1 , Pier Mannuccio Mannucci2
  • 1Immunohematology and Transfusion Center, Department of Pathology and Laboratory Medicine, University Hospital of Parma, Italy
  • 2Angelo Bianchi Bonomi Hemophilia and Thrombosis Center, Department of Medicine and Medical Specialties, University of Milan and IRCCS Maggiore Hospital, Mangiagalli and Regina Elena Foundation, Milan, Italy
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Publikationsverlauf

Publikationsdatum:
09. Dezember 2009 (online)

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ABSTRACT

It is well known that exposure to particulate air pollutants is associated with the development of adverse health effects. In particular, there is growing evidence of a close relationship between increased levels of environmental pollutants and cardiovascular disease. Particle exposure may trigger acute cardiac events as well as promote the chronic development of cardiovascular disorders. Several biological mechanisms have been suggested to explain the important effect of air pollution on cardiovascular morbidity and mortality, although the exact pathways are not fully understood. The literature data on the short-term and long-term cardiovascular effects of particulate air pollutants are discussed in this review from a clinical and mechanistic point of view.

KEYWORDS

Air pollution - thrombosis - cardiovascular disease

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Massimo FranchiniM.D. 

Immunohematology and Transfusion Center, Department of Pathology and Laboratory Medicine

University Hospital of Parma, Italy

eMail: mfranchini@ao.pr.it