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Dtsch Med Wochenschr 2009; 134: S376-S380
DOI: 10.1055/s-0029-1243045
DOI: 10.1055/s-0029-1243045
Übersicht | Review article
Pneumologie
© Georg Thieme Verlag KG Stuttgart · New York
Gibt es Vorteile der Fixkombination bei der Therapie von Asthma bronchiale hinsichtlich der Verträglichkeit und Sicherheit?
Are there any advantages of a fixed combination in the treatment of asthma with respect to safety and tolerability?Further Information
Publication History
eingereicht: 16.2.2009
akzeptiert: 23.7.2009
Publication Date:
25 November 2009 (online)
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Schlüsselwörter
Fixkombination - Adhärenz - Compliance
Keywords
fixed combination - adherence - compliance
Literatur
- 1 Castle W, Fuller R, Hall J, Palmer J. Serevent nationwide surveillance study: comparison of salmeterol with salbutamol in asthmatic patients who require regular bronchodilator treatment. BMJ. 1993; 306 1034-1037
- 2 Cooper P R, Panettieri Jr R A. Steroids completely reverse albuterol-induced beta(2)-adrenergic receptor tolerance in human small airways. J Allergy Clin Immunol. 2008; 122 734-740
- 3 Hasford J, Virchow J C. Excess mortality in patients with asthma on long-acting beta2-agonists. Eur Respir J. 2006; 28 900-902
- 4 Huchon G, Magnussen H, Chuchalin A, Dymek L, Gonod F B, Bousquet J. Lung function and asthma control with beclomethasone and formoterol in a single inhaler. Respir Med. 2008; 103 41-49
- 5 Inman W H, Adelstein A M. Asthma mortality and pressurised aerosols. Lancet. 1969; 2 693
- 6 Mcivor R A, Pizzichini E, Turner M O, Hussack P, Hargreave F E, Sears M R. Potential masking effects of salmeterol on airway inflammation in asthma. Am J Respir Crit Care Med. 1998; 158 924-930
- 7 Milgrom H, Bender B, Ackerson L, Bowry P, Smith B, Rand C. Noncompliance and treatment failure in children with asthma. J Allergy Clin Immunol. 1996; 98 1051-1057
- 8 Nelson H S, Weiss S T, Bleecker E R, Yancey S W, Dorinsky P M. SMART Study Group . The Salmeterol Multicenter Asthma Research Trial: a comparison of usual pharmacotherapy for asthma or usual pharmacotherapy plus salmeterol. Chest. 2006; 129 15-26
- 9 Papi A, Paggiaro P L, Nicolini G, Vignola A M, Fabbri L M. Inhaled Combination Asthma Treatment versus SYmbicort (ICAT SY) Study Group . Beclomethasone/formoterol versus budesonide/formoterol combination therapy in asthma. Eur Respir J. 2007; 29 682-689
-
10 Ratner B.
. In: Abramson HA, ed Treatment of Asthma. London; Baillière, Tindall & Cox, Ltd 1952: xiv, 752 - 11 Salpeter S R, Ormiston T M, Salpeter E E. Meta-analysis: respiratory tolerance to regular beta2-agonist use in patients with asthma. Ann Intern Med. 2004; 140 802-813
- 12 Sears M R, Taylor D R, Print C G. et al . Regular inhaled beta-agonist treatment in bronchial asthma. Lancet. 1990; 336 1391-1396
- 13 Thongngarm T, Silkoff P E, Kossack W S, Nelson H S. Hydrofluoroalkane-134A beclomethasone or chlorofluorocarbon fluticasone: effect on small airways in poorly controlled asthma. J Asthma. 2005; 42 257-263
- 14 Wolfe J, Laforce C, Friedman B. et al . Formoterol, 24 microg bid, and serious asthma exacerbations: similar rates compared with formoterol, 12 microg bid, with and without extra doses taken on demand, and placebo. Chest. 2006; 129 27-38
Prof. Dr. Christian Virchow
Klinik und Poliklinik für Innere Medizin,
Abteilung für Pneumologie, Medizinische
Fakultät der Universität Rostock
Ernst-Heydemann-Straße
6
Phone: 0381/4947-460
Fax: 0381/4947-392
Email: j.c.virchow@med.uni-rostock.de