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Planta Med 2000; 66(4): 384-385
DOI: 10.1055/s-0029-1243139
DOI: 10.1055/s-0029-1243139
Letter
© Georg Thieme Verlag Stuttgart · New York
Sipandinolide: A Butenolide Including a Novel Type of Carbon Skeleton from Siparuna andina
Further Information
Publication History
Received: June 22, 1999
Accepted: July 17, 1999
Publication Date:
24 November 2009 (online)
![](https://www.thieme-connect.de/media/plantamedica/200004/lookinside/thumbnails/10.1055-s-0029-1243139-1.jpg)
Abstract
From a lipophilic extract of leaves of Siparuna andina (Monimiaceae), which exhibited antiplasmodial activity in vitro, two new compounds have been isolated: sipandinolide (1), a compound with a novel type of carbon skeleton and (–)-cis-3- acetoxy-4′,5,7-trihydroxyflavanone (2). Their structures were established by spectroscopic methods; 2 showed moderate antiplasmodial activity whereas 1 was inactive.
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Dr. Kristina Jenett-Siems
Institut für Pharmazie (Pharmazeutische Biologie)
Freie Universität Berlin
Königin-Luise-Str. 2–4
14195 Berlin
Germany
Email: kjsiems@zedat.fu-berlin.de
Phone: 030-8383720