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Exp Clin Endocrinol Diabetes 2010; 118(6): 364-367
DOI: 10.1055/s-0029-1243623
Short Communication

© J. A. Barth Verlag in Georg Thieme Verlag KG Stuttgart · New York

Glycaemic Control is Correlated with Well-Being Index (WHO-5) in Subjects with Type 2 Diabetes

N. Papanas1 , A. Tsapas2 , 3 , K. Papatheodorou1 , D. Papazoglou1 , E. Bekiari2 , M. Sariganni2 , K. Paletas2 , E. Maltezos1
  • 1Outpatient Clinic of Obesity, Diabetes and Metabolism in the Second Department of Internal Medicine, Democritus University of Thrace, Greece
  • 2Second Medical Department, Aristotle University of Thessaloniki, Greece
  • 3Harris Manchester Medical Academy, Oxford, UK
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Publication History

received 05.10.2009 first decision 22.11.2009 accepted 02.12.2009

Publication Date:
05 February 2010 (online)

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Abstract

The aim of this study was to examine the potential correlation of WHO-5 well-being index with glycaemic control and chronic complications in subjects with type 2 diabetes. The study included 156 subjects (73 men, mean age 64.05±9.11 years, mean diabetes duration 12.22±5.61 years). Well-being was assessed by the WHO-5 score via a validated questionnaire comprising 5 questions (Q1-Q5). HbA1c showed a significant negative correlation with overall WHO-5 score (rs=−0.248, p=0.002) and individual Q1–Q4 scores (rs=−0.262, p=0.001; rs=−0.248, p=0.002; rs=−0.207, p=0.009 and rs=−0.169, p=0.035 respectively). Subjects with adequate glycaemic control (HbA1c < 7%, n=67) had a significantly higher WHO-5 score in comparison to those with inadequate glycaemic control (HbA1c ≥ 7%, n=89) (mean±SD: 19.69±5.47 vs. mean±SD: 17.11±6.38, p=0.011). Finally, WHO-5 score was significantly (p=0.013) lower in subjects with neuropathic pain than in those without neuropathic pain. Conclusions: In type 2 diabetic subjects, glycaemic control shows a significant correlation with well-being, while neuropathic pain is associated with lower well-being score.

Key words

diabetes mellitus - quality of life - glycaemic control - WHO-5 - neuropathic pain

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Correspondence

Dr. N. Papanas

Democritus University of Thrace

68100 Alexandroupolis

Greece

Phone: +30 6977 544337

Fax: +30 25510 74723

Email: papanasnikos@yahoo.gr