Kardiologie up2date 2010; 6(2): 106-116
DOI: 10.1055/s-0029-1244221
Hotline – Kardiovaskuläre Notfälle

© Georg Thieme Verlag KG Stuttgart · New York

Blutzuckereinstellung auf Intensivstation – intensiviert oder konservativ?

Christian  Heinrich, Mathias  Burgmaier, Nikolaus  Marx
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Publication History

Publication Date:
06 July 2010 (online)

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Abstract

Tight blood glucose control in critical ill patients has been discussed controversially during the last years. Several studies have recently demonstrated a reduction of morbidity and mortality in critical ill patients treated with tight glycemic control, while others could not confirm theses findings. In addition, various studies targeting elevated glucose levels by insulin therapy in patients with acute coronary syndrome showed only mixed results. Moreover, recent data suggest that hypoglycemia is associated with an increased mortality rate in patients with ACS and several studies have shown that hypoglycemia is an independent risk factor for overall mortality in patients with severe sepsis and septic shock. The present article reviews current data on tight glucose control in critical ill patients and analyzes their significance for clinical practice.

Kernaussage

Aufgrund der vorliegenden Datenlage erscheint bei Patienten mit ACS und erwachsenen, kritisch kranken Patienten eine konventionelle Blutzuckereinstellung (Zielbereich 144 – 180 mg/dl bzw. 8,0 – 10,0 mmol/l) unter Vermeidung von Hypoglykämien gerechtfertigt.

Literatur

Dr. med. Christian Heinrich

Medizinische Klinik I – Kardiologie, Pneumologie und Angiologie
Universitätsklinikum Aachen

Pauwelsstraße 30
52074 Aachen

Email: cheinrich@ukaachen.de