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DOI: 10.1055/s-0029-1245627
© Georg Thieme Verlag KG Stuttgart · New York
Aktueller Stand der MR-gesteuerten Prostata-Interventionen
MR-Guided Interventions of the Prostate Gland: a Literature ReviewPublikationsverlauf
eingereicht: 15.2.2010
angenommen: 2.7.2010
Publikationsdatum:
19. August 2010 (online)
![](https://www.thieme-connect.de/media/roefo/201011/lookinside/thumbnails/10.1055-s-0029-1245627-1.jpg)
Zusammenfassung
In den letzen Jahren spielt die MRT in der Diagnostik und Therapie des Prostatakarzinoms eine immer wichtigere Rolle. Die MRT erlaubt neben der Abgrenzung der anatomischen Strukturen auch die Lokalisation möglicher Tumoren durch die Verwendung von T 2-gewichteten Sequenzen, der Spektroskopie sowie dynamischer Untersuchungen. Die gute Abgrenzbarkeit der Tumoren erlaubt eine sichere Durchführung von Prostatainterventionen, wie Biopsien, Brachytherapie oder verschiedenen lokalen Thermotherapien. Durch den zusätzlichen Einsatz von Robotersystemen kann die Genauigkeit der Interventionen erhöht werden. Aufgrund der Vorteile der MR-Bildgebung ist zu erwarten, dass MR-gesteuerte Prostatainterventionen in der Zukunft eine zunehmende Rolle spielen werden.
Abstract
In recent years MR imaging has played an increasingly important role in the diagnosis and treatment of prostate cancer. MR imaging of the prostate allows clear delineation of the anatomic structures and prostate tumors using T 2-weighted images combined with spectroscopy and dynamic examinations. The advantages of MRI make it possible to perform interventions, like biopsies, brachytherapy or different local therapies of the prostate gland. MRI robotic assistance will improve the accuracy of the interventions. Due to the advantages of MR imaging, MR-guided prostate interventions will play a greater role in the future.
Key words
prostate - ablation procedures - biopsy - interventional MR - interventional procedures
Literatur
- 1 Sakr W A, Grignon D J, Crissman J D et al. High grade prostatic intraepithelial neoplasia (HGPIN) and prostatic adenocarcinoma between the ages of 20 – 69: an autopsy study of 249 cases. In vivo. 1994; 8 439-443
- 2 Mueller-Lisse U L, Hofstetter A. Urologische Diagnostik des Prostatakarzinoms. Radiologe. 2003; 43 432-440
- 3 Andriole G L, Crawford E D, Grubb 3 rd R L et al. Mortality results from a randomized prostate-cancer screening trial. The New England journal of medicine. 2009; 360 1310-1319
- 4 Naughton C K, Miller D C, Mager D E et al. A prospective randomized trial comparing 6 versus 12 prostate biopsy cores: impact on cancer detection. J Urol. 2000; 164 388-392
- 5 Tempany C, Straus S, Hata N et al. MR-guided prostate interventions. J Magn Reson Imaging. 2008; 27 356-367
- 6 Stewart C S, Leibovich B C, Weaver A L et al. Prostate cancer diagnosis using a saturation needle biopsy technique after previous negative sextant biopsies. J Urol. 2001; 166 86-91 ; discussion 91 – 82
- 7 Pegios W, Bentas W, Wittmann L et al. Kernspintomographisches Staging des Prostatakarzinoms mittels kombinierter Endorektal-Body-Phased-Array-Spule und histopathologische Korrelation. Fortschr Röntgenstr. 2003; 175 1660-1666
- 8 Engelbrecht M R, Jager G J, Laheij R J et al. Local staging of prostate cancer using magnetic resonance imaging: a meta-analysis. Eur Radiol. 2002; 12 2294-2302
- 9 Stanka M, Eltze E, Semjonow A et al. Spektroskopische Bildgebung (1 H-MR-CSI) der Prostata: Sequenzoptimierung und Korre-lation mit histopathologischen Untersuchungen. Fortschr Röntgenstr. 2000; 172 623-629
- 10 Scheidler J, Vogel M, Gross P et al. Kombinierte MRT und MRS beim Prostatakarzinom: Beschleunigung und Verbesserung durch Suszeptibilitätsangleichung. Fortschr Röntgenstr. 2009; 181 531-535
- 11 Wiesinger B, Lichy M P, Nagele U et al. MR-Befundmuster der Prostata bei Patienten mit CPP Syndrom (chronic pelvic pain syndrome). Fortschr Röntgenstr. 2008; 180 621-630
- 12 Franiel T, Ludemann L, Taupitz M et al. Pharmakokinetische MRT der Prostata: Parameter zur Unterscheidung von Low-grade- und High-grade-Prostatakarzinomen. Fortschr Röntgenstr. 2009; 181 536-542
- 13 Kemper J, Sinkus R, Lorenzen J et al. MR-Elastographie der Prostata: Erste In-vivo-Anwendung. Fortschr Röntgenstr. 2004; 176 1094-1099
- 14 Prando A, Kurhanewicz J, Borges A P et al. Prostatic biopsy directed with endorectal MR spectroscopic imaging findings in patients with elevated prostate specific antigen levels and prior negative biopsy findings: early experience. Radiology. 2005; 236 903-910
- 15 Kaplan I, Oldenburg N E, Meskell P et al. Real time MRI-ultrasound image guided stereotactic prostate biopsy. Magn Reson Imaging. 2002; 20 295-299
- 16 Gupta S, Nguyen H, Morello F et al. Various Approaches for CT-guided Percutaneous Biopsy of Deep Pelvic Lesions: Anatomic and Technical Considerations. Radiographics. 2004; 24 175-189
- 17 D’Amico A V, Tempany C M, Cormack R et al. Transperineal magnetic resonance image guided prostate biopsy. J Urol. 2000; 164 385-387
- 18 Hata N, Jinzaki M, Kacher D et al. MR imaging-guided prostate biopsy with surgical navigation software: device validation and feasibility. Radiology. 2001; 220 263-268
- 19 Zangos S, Eichler K, Engelmann K et al. MR-guided transgluteal biopsies with an open low-field system in patients with clinically suspected prostate cancer: technique and preliminary results. Eur Radiol. 2005; 15 174-182
- 20 Beyersdorff D, Winkel A, Hamm B et al. MR imaging-guided prostate biopsy with a closed MR unit at 1.5T: initial results. Radiology. 2005; 234 576-581
- 21 Engelhard K, Hollenbach H P, Kiefer B et al. Prostate biopsy in the supine position in a standard 1.5-T scanner under real time MR-imaging control using a MR-compatible endorectal biopsy device. Eur Radiol. 2006; 16 1237-1243
- 22 Zangos S, Herzog C, Eichler K et al. MR-compatible assistance system for punction in a high-field system: device and feasibility of transgluteal biopsies of the prostate gland. Eur Radiol. 2007; 17 1118-1124
- 23 Lewin J S, Duerk J L, Jain V R et al. Needle localization in MR-guided biopsy and aspiration: effects of field strength, sequence design, and magnetic field orientation. Am J Roentgenol. 1996; 166 1337-1345
- 24 Adam G, Bucker A, Nolte-Ernsting C et al. Interventional MR imaging: percutaneous abdominal and skeletal biopsies and drainages of the abdomen. Eur Radiol. 1999; 9 1471-1478
- 25 Cormack R A, D’Amico A V, Hata N et al. Feasibility of transperineal prostate biopsy under interventional magnetic resonance guidance. Urology. 2000; 56 663-664
- 26 Zangos S, Kiefl D, Eichler K et al. MRT-gezielte perkutane Biopie bei unklaren fokalen Leberläsionen: Technik und Ergebnisse. Fortschr Röntgenstr. 2003; 175 688-694
- 27 Franiel T, Fritzsche F, Staack A et al. [Histopathologic quality of prostate core biopsy specimens: comparison of an MR-compatible biopsy needle and a ferromagnetic biopsy needle used for ultrasound-guided prostate biopsy] Histopathologische Qualität von Prostatazylindern: Vergleich einer MR-kompatiblen Biopsienadel mit einer im Ultraschall eingesetzten ferromagnetischen Biopsienadel. Fortschr Röntgenstr. 2006; 178 1212-1218
- 28 Duckwiler G, Lufkin R B, Hanafee W N. MR-directed needle biopsies. Radiol Clin North Am. 1989; 27 255-263
- 29 Hambrock T, Futterer J J, Huisman H J et al. Thirty-two-channel coil 3 T magnetic resonance-guided biopsies of prostate tumor suspicious regions identified on multimodality 3 T magnetic resonance imaging: technique and feasibility. Invest Radiol. 2008; 43 686-694
- 30 Van Gellekom M P, Moerland M A, Battermann J J et al. MRI-guided prostate brachytherapy with single needle method – a planning study. Radiother Oncol. 2004; 71 327-332
- 31 Prada P J, Gonzalez H, Fernandez J et al. High-dose-rate intensity modulated brachytherapy with external-beam radiotherapy improves local and biochemical control in patients with high-risk prostate cancer. Clin Transl Oncol. 2008; 10 415-421
- 32 D’Amico A V, Cormack R, Tempany C M et al. Real-time magnetic resonance image-guided interstitial brachytherapy in the treatment of select patients with clinically localized prostate cancer. Int J Radiat Oncol Biol Phys. 1998; 42 507-515
- 33 Chen L, Price R A, Wang Jr L et al. MRI-based treatment planning for radiotherapy: dosimetric verification for prostate IMRT. International journal of radiation oncology, biology, physics. 2004; 60 636-647
- 34 Tanaka O, Hayashi S, Matsuo M et al. MRI-based preplanning in low-dose-rate prostate brachytherapy. Radiother Oncol. 2008; 88 115-120
- 35 Polo A, Cattani F, Vavassori A et al. MR and CT image fusion for postimplant analysis in permanent prostate seed implants. International journal of radiation oncology, biology, physics. 2004; 60 1572-1579
- 36 Menard C, Susil R C, Choyke P et al. MRI-guided HDR prostate brachytherapy in standard 1.5 T scanner. Int J Radiat Oncol Biol Phys. 2004; 59 1414-1423
- 37 Susil R C, Camphausen K, Choyke P et al. System for prostate brachytherapy and biopsy in a standard 1.5T MRI scanner. Magn Reson Med. 2004; 52 683-687
- 38 Hurwitz M D, Cormack R, Tempany C M et al. Three-dimensional real-time magnetic resonance-guided interstitial prostate brachytherapy optimizes radiation dose distribution resulting in a favorable acute side effect profile in patients with clinically localized prostate cancer. Techniques in urology. 2000; 6 89-94
- 39 Albert M, Tempany C M, Schultz D et al. Late genitourinary and gastrointestinal toxicity after magnetic resonance image-guided prostate brachytherapy with or without neoadjuvant external beam radiation therapy. Cancer. 2003; 98 949-954
- 40 Nguyen P L, Chen M H, D’Amico A V et al. Magnetic resonance image-guided salvage brachytherapy after radiation in select men who initially presented with favorable-risk prostate cancer: a prospective phase 2 study. Cancer. 2007; 110 1485-1492
- 41 Vogl T J, Straub R, Lehnert T et al. Perkutane Thermoablation von Lungenmetastasen – Erfahrungen mit dem Einsatz der LITT, der Radiofrequenzablation (RFA) und Literaturübersicht[Percutaneous Thermoablation of Pulmonary Metastases. Fortschr Röntgenstr. 2004; 176 1658-1666
- 42 Vogl T J, Mack M G, Muller P K et al. Interventional MR: interstitial therapy. Eur Radiol. 1999; 9 1479-1487
- 43 Peters R D, Chan E, Trachtenberg J et al. Magnetic resonance thermometry for predicting thermal damage: an application of interstitial laser coagulation in an in vivo canine prostate model. Magn Reson Med. 2000; 44 873-883
- 44 Nau W H, Diederich C J, Ross A B et al. MRI-guided interstitial ultrasound thermal therapy of the prostate: a feasibility study in the canine model. Med Phys. 2005; 32 733-743
- 45 Josan S, Bouley D M, Bosch van den M et al. MRI-guided cryoablation: In vivo assessment of focal canine prostate cryolesions. J Magn Reson Imaging. 2009; 30 169-176
- 46 Tazaki H, Deguchi N, Baba S et al. Magnetic resonance imaging following microwave thermotherapy, laser ablation and transurethral resection in patients with BPH. Urologe A. 1995; 34 105-109
- 47 Mueller-Lisse U G, Thoma M, Faber S et al. Coagulative interstitial laser-induced thermotherapy of benign prostatic hyperplasia: online imaging with a T 2-weighted fast spin-echo MR sequence – experience in six patients. Radiology. 1999; 210 373-379
- 48 Chen J C, Moriarty J A, Derbyshire J A et al. Prostate cancer: MR imaging and thermometry during microwave thermal ablation-initial experience. Radiology. 2000; 214 290-297
- 49 Pauly K B, Diederich C J, Rieke V et al. Magnetic resonance-guided high-intensity ultrasound ablation of the prostate. Top Magn Reson Imaging. 2006; 17 195-207
- 50 Kettenbach J, Kronreif G, Figl M et al. Robot-assisted biopsy using computed tomography-guidance: initial results from in vitro tests. Invest Radiol. 2005; 40 219-228
- 51 Felden A, Vagner J, Hinz A et al. ROBITOM-robot for biopsy and therapy of the mamma. Biomed Tech. 2002; 47 2-5
- 52 Hempel E, Fischer H, Gumb L et al. An MRI-compatible surgical robot for precise radiological interventions. Comput Aided Surg. 2003; 8 180-191
- 53 Dimaio S P, Pieper S, Chinzei K et al. Robot-assisted needle placement in open MRI: System architecture, integration and validation. Comput Aided Surg. 2007; 12 15-24
- 54 Susil R C, Krieger A, Derbyshire J A et al. System for MR image-guided prostate interventions: canine study. Radiology. 2003; 228 886-894
- 55 Fischer G S, DiMaio S P, Iordachita I I et al. Robotic assistant for transperineal prostate interventions in 3 T closed MRI. Med Image Comput Comput Assist Interv Int Conf Med Image Comput Comput Assist Interv. 2007; 10 425-433
Dr. Stephan Zangos
Institut für Diagnostische und Interventionelle Radiologie, J.-W.-Goethe-Universität Frankfurt
Theodor-Stern-Kai 7
60596 Frankfurt
Telefon: ++ 49/63 01/72 77
Fax: ++ 49/63 01/72 58
eMail: Zangos@em.uni-frankfurt.de