PSYCH up2date, Table of Contents Psychiatrie und Psychotherapie up2date 2009; 3(5): e16-e18DOI: 10.1055/s-0029-39621 Pro/Con-Debatte © Georg Thieme Verlag KG Stuttgart ˙ New York Pro und Contra: Metaanalysen vs. Large simple Trials/große naturalistische Studien Recommend Article Abstract All articles of this category Full Text References Literatur 01 Leucht S . Corves C . Arbter D . et al . Second-generation versus first-generation antipsychotic drugs for schizophrenia: a meta-analysis. Lancet. 2009; 373 31-41 02 Leucht S . Komossa K . Rummel-Kluge C . et al . A meta-analysis of head to head comparisons of second generation antipsychotics in the treatment of schizophrenia. Am J Psychiatry. 2009; 166 152-163 03 Heres S . Davis J . Maino K . et al . Why olanzapine beats risperidone, risperidone beats quetiapine, and quetiapine beats olanzapine: An exploratory analysis of head-to-head comparison studies of second-generation antipsychotics. Am J Psychiatry. 2006; 163, no 2 185-194 04 Lieberman JA . Stroup TS . McEvovy JP . et al . Effectiveness of antipsychotic drugs in patients with chronic schizophrenia. N Engl J Med. 2005; 353, no. 12 1209-1223 05 Jones PB . Barnes TRE . Davies L . et al . Randomized controlled trial of the effect on quality of life of second- vs first-generation antipsychotic drugs in schizophrenia - cost utility of the latest antipsychotic drugs in schizophrenia study (CUtLASS 1). Arch Gen Psychiatry. 2006; 63, no. 10 1079-1086 06 Kahn RS . Fleischhacker WW . Boter H . et al . Effectiveness of antipsychotic drugs in first-episode schizophrenia and schizophreniform disorder: an open randomised clinical trial. Lancet. 2008; 371, no. 9618 1085-1097