Cyberknife®-Chirurgie mit dem Strahlenmesser: eine neue Behandlungsalternative für Patienten mit inoperablen Metastasen

Zusammenfassung

Für Patienten mit nicht resektablen Fernmetastasen existieren mittlerweile eine Reihe von alternativen Behandlungsmöglichkeiten, wie zum Beispiel die Radiofrequenzablation, Laser-induzierte Thermoablation oder auch die stereotaktische Bestrahlung. Die Anwendungen dieser Verfahren ist häufig limitiert durch ihre Invasivität und die zu erwartende Verfahrens-assoziierte Morbidität. Für die sterotaktischen Bestrahlungsverfahren mussten Patienten bislang ausgesprochene körperliche Unannehmlichkeiten durch die notwendigen Fixierungen und Ruhigstellungen beweglicher Organe (Lunge, Leber) in Kauf nehmen. Mit der Entwicklung der Cyberknife-Chirurgie, einer Computerbild-gesteuerten, hochselektiven, roboterbasierten Radiotherapie sind diese Probleme beseitigt. Mit dieser neuen Technik lassen sich Metastasen in einer einzigen ambulanten Behandlung erfolgreich radiochirurgisch behandeln.

Abstract

Patients with non-resectable metastases of various diseases are today treated by one of several different techniques, such as radiofrequency ablation, laser-induced thermoablation or stereotactic radiotherapy. Frequently, the employment of these therapeutic strategies is limited due to their invasiveness and treatment-associated morbidity. Furthermore, stereotactic radiotherapy is associated with a high degree of patient discomfort due to the necessary fixation of moving inner organs (lung, liver). With the development of the cyberknife radiosurgery technique, an image-guided, superselective, robot-based radiotherapy, these problems seem to be resolved. With this technique, metastases may be treated in an outpatient single-treatment setting.

Schlüsselwörter

Lebermetastase - lokale Tumorablation - multimodale Therapie - Radiotherapie - RFA

Key words

liver metastasis - local tumour ablation - multimodal treatment - radiotherapy - radiofrequency ablation (RFA)

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