DMW - Deutsche Medizinische Wochenschrift, Inhaltsverzeichnis Dtsch Med Wochenschr 2010; 135(23): 1198-1200DOI: 10.1055/s-0030-1247868 Kommentar | Commentary Infektiologie, Immuntherapie © Georg Thieme Verlag KG Stuttgart · New York Pneumokokkenimpfung und Serotypen-Replacement: Brauchen wir ein neues Impf(stoff)konzept? Pneumococcal vaccination and serotype replacement: Do we need new vaccination concepts? S. Kenzel1 , 2 , M. Hufnagel1 , R. Berner1 , P. Henneke1 , 2 1Zentrum für Kinder- und Jugendmedizin, Universitätsklinikum Freiburg 2Centrum für Chronische Immundefizienz, Universitätsklinikum Freiburg Artikel empfehlen Abstract Artikel einzeln kaufen Schlüsselwörter invasive Pneumokokkeninfektion - Pneumokokken-Serotypen - Impfung - Polysaccharid-Impfstoffe - Konjugatvakzine - Serotypen-Replacement Keywords invasive pneumococcal disease - pneumococcal serotypes - vaccination - polysaccharide vaccine - conjugate vaccine - serotype replacement Volltext Referenzen Literatur 1 Invasive pneumococcal disease in children 5 years after conjugate vaccine introduction. Morb Mortal Wkly Rep. 2008; 57 144-148 2 Bae S, Lee K. Distribution of capsular serotypes and macrolide resistance mechanisms among macrolide-resistant Streptococcus pneumoniae isolates in Korea. Diagn Microbiol Infect Dis. 2009; 63 213-216 3 Barocchi M A, Censini S, Rappuoli R. Vaccines in the era of genomics: the pneumococcal challenge. Vaccine. 2007; 25 2963-2673 4 Black S, Lieu T A, Ray G T, Capra A, Shinefield H R. Assessing costs and cost effectiveness of pneumococcal disease and vaccination within Kaiser Permanente. Vaccine,. 2000; 19 Suppl 1, S83-86 5 Black S, Shinefield H. et al . Efficacy, safety and immunogenicity of heptavalent pneumococcal conjugate vaccine in children. Pediatr Infect Dis J. 2000; 19 187-195 6 Choi E H, Kim S H, Eun B W. et al . Streptococcus pneumoniae serotype 19A in children, South Korea. Emerg Infect Dis. 2008; 14 275-281 7 Douglas R M, Hansman D, Miles H B, Paton J C. Pneumococcal carriage and type-specific antibody. Am J Dis Child. 1986; 140 1183-1185 8 Go C, Asnis D S, Saltzman H. Pneumococcal pericarditis since 1980. Clin Infect Dis. 1998; 27 1338-1340 9 Hamel J, Charland N, Pineau I. et al . Prevention of pneumococcal disease in mice immunized with conserved surface-accessible proteins. Infect Immun. 2004; 72 2659-2670 10 Hicks L A, Harrison L H, Flannery B. et al . Incidence of pneumococcal disease due to non pneumococcal conjugate vaccine (PCV7) serotypes in the United States during the era of widespread PCV7 vaccination, 1998 – 2004. J Infect Dis. 2007; 196 1346-1354 11 Huss A, Scott P, Stuck A E, Trotter C, Egger M. Efficacy of pneumococcal vaccination in adults. CMAJ. 2009; 180 48-58 12 Imohl M, Reinert R R, van der Linden M. Regional differences in serotype distribution, pneumococcal vaccine coverage, and antimicrobial resistance of invasive pneumococcal disease among German federal states. Int J Med Microbiol. 2009; 300 237-247 13 Juhn Y J, Kita H, Yawn B P. et al . Increased risk of serious pneumococcal disease in patients with asthma. J Allergy Clin Immunol. 2008; 122 719-723 14 Klacsmann P G, Bulkley B H, Hutchins G M. The changed spectrum of purulent pericarditis. Am J Med. 1977; 63 666-673 15 Kyaw M H, Lynfield R, Schaffner W. et al . Effect of introduction of the pneumococcal conjugate vaccine on drug-resistant Streptococcus pneumoniae. N Engl J Med. 2006; 354 1455-1463 16 Levine O S, Farley M, Harrison L H. et al . Risk factors for invasive pneumococcal disease in children. Pediatrics. 1999; 103 E28 17 Malley R. Antibody and cell-mediated immunity to Streptococcus pneumoniae. J Mol Med. 2010; 88 135-142 18 Obaro S K, Adegbola R A, Banya W A, Greenwood B M. Carriage of pneumococci after pneumococcal vaccination. Lancet. 1996; 348 271-272 19 Ogunniyi A D, Grabowicz M, Briles D E, Cook J, Paton J C. Development of a vaccine against invasive pneumococcal disease based on combinations of virulence proteins of Streptococcus pneumoniae. Infect Immun. 2007; 75 350-357 20 Pletz M W, Maus U, Hohlfeld J M, Lode H, Welte T. Pneumokokkenimpfung: Konjugatimpfstoff induziert Herdenimmunität und reduziert Antibiotikaresistenz. Dtsch med Wochenschr. 2008; 133 358-362 21 Reinert R R, Haupts S, van der Linden M. et al . Invasive pneumococcal disease in adults in North-Rhine Westphalia, Germany, 2001 – 2003. Clin Microbiol Infect. 2005; 11 985-991 22 Spratt B G, Greenwood B M. Prevention of pneumococcal disease by vaccination. Lancet. 2000; 356 1210-1211 23 Stephens D S, Zughaier S M. et al . Incidence of macrolide resistance in Streptococcus pneumoniae after introduction of the pneumococcal conjugate vaccine. Lancet. 2005; 365 855-863 PD Dr. med. Philipp Henneke Centrum für Chronische Immundefizienz, Zentrum für Kinderheilkunde und Jugendmedizin Mathildenstr. 1 79106 Freiburg Telefon: 0761/270-7764 Fax: 0761/270-7760 eMail: philipp.henneke@uniklinik-freiburg.de
