Thorac Cardiovasc Surg 2011; 59(4): 207-212
DOI: 10.1055/s-0030-1250346
Original Cardiovascular/Society Paper

© Georg Thieme Verlag KG Stuttgart · New York

Persistent Atrial Fibrillation Ablation Concomitant to Coronary Surgery[*]

S. Geidel1 , M. Lass1 , K. Krause2 , C. Schneider2 , S. Boczor2 , K.-H. Kuck2 , J. Ostermeyer1 , M. Schmoeckel1
  • 1Department of Cardiac Surgery, Asklepios Klinik St. Georg, Hamburg, Germany
  • 2Department of Cardiology, Asklepios Klinik St. Georg, Hamburg, Germany
Further Information

Publication History

received June 3, 2010

Publication Date:
15 March 2011 (online)

Abstract

Objective: This analysis was undertaken to evaluate the results of persistent atrial fibrillation (pAF) ablation procedures concomitant to coronary surgery and to identify the risk factors for pAF recurrence. Methods: Since 2001, a total of 126 consecutive patients with pAF (duration: 0.5–33 years) underwent ablation concomitant to coronary surgery (isolated or in combination with valve surgery), whereby two encircling isolation lesions around the left and the right pulmonary veins and a connecting lesion between both was created using radiofrequency ablation. Patients were reevaluated at discharge, 3 months and 3 years after surgery. Results: Survivals at the time of reexamination were 96.8, 95.1 and 94.7 %, respectively. Stable sinus rhythm (SR) could be documented in 66.4, 75.1 and 75.9 % of surviving patients. Long-term pAF before surgery and a larger left atrium (LA) were predictive of postoperative pAF return (p < 0.01). Statistical analysis demonstrated a cut-off point of 5 years for pAF and 50 mm for LA diameter: 89.1 % of patients with pAF duration of < 5 years and 86.2 % of patients with LA size of ≤ 50 mm were in stable SR at late follow-up. Cardiac rhythm at 3 months was predictive for long-term rhythm prognosis (p < 0.01). Age, gender and concomitant diseases (e.g. arterial hypertension, diabetes, renal insufficiency), and the underlying cause of heart disease did not significantly influence the postoperative cardiac rhythm. Conclusions: The duration of pAF and the LA size are the most reliable preoperative variables to predict the success rate of ablation in patients undergoing coronary surgery. The probability of re-establishing stable SR is excellent when pAF duration is short and LA size is small.

1 Presented at the 39th Annual Meeting of the German Society for Thoracic and Cardiovascular Surgery, Stuttgart, February 14–17, 2010 (V 171).

References

  • 1 Brodell G K, Cosgrove D, Schiavone W, Underwood D A, Loop F D. Cardiac rhythm and conduction disturbances in patients undergoing mitral valve surgery.  Cleve Clin J Med. 1991;  58 397-399
  • 2 Benjamin E J, Wolf P A, D'Agostino R B, Silbershatz H, Kannel W B, Levy D. Impact of atrial fibrillation on the risk of death: the Framingham heart study.  Circulation. 1998;  98 946-952
  • 3 Cox J L, Schuessler R B, Lappas D G, Boineau J P. An 8 œ year clinical experience with surgery for atrial fibrillation.  Ann Thorac Surg. 1996;  224 267-275
  • 4 Melo J, Andragao P, Neves J, Ferreira M, Timoteo A, Santiago T et al. Endocardial and epicardial radiofrequency ablation in the treatment of atrial fibrillation with a new intraoperative device.  Eur J Cardiothorac Surg. 2000;  18 182-186
  • 5 Benussi S, Pappone C, Nascimbene S et al. A simple way to treat chronic atrial fibrillation during mitral valve surgery: the epicardial radiofrequency approach.  Eur J Cardiothorac Surg. 2000;  17 524-529
  • 6 Fuster V, Rydén L E, Cannom D S et al. ACC/AHA/ESC2006 guidelines for the management of patients with atrial fibrillation: A report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines and the European Society of Cardiology Committee for Practice Guidelines (Writing Committee to Revise the 2001 Guidelines for the Management of Patients with Atrial Fibrillation): Developed in collaboration with the European Heart Rhythm Association and the Heart Rhythm Society.  Circulation. 2006;  114 (7) e257-354
  • 7 Moe G K. On the multiple wavelet hypothesis of atrial fibrillation.  Arch Int Pharmacodyn Ther. 1962;  140 183-188
  • 8 Allessie M, Lammers W J E P, Bunke F I, Hollen J. Experimental Evaluation of Moe's multiple Wavelet Hypothesis of atrial Fibrillation.. In: Zipes D, Jalife J, eds. Cardiac Electrophysiology and Arrhythmias.. New York: Cruno and Straiton; 1985: 265-275
  • 9 Wijffels M C E F, Kirchhof C J H J, Doland R. Atrial fibrillation begets atrial fibrillation.  Circulation. 1995;  92 1954-1968
  • 10 Haissaguerre M, Jais P, Shah D C et al. Spontaneous initiation of atrial fibrillation by ectopic beats originating from the pulmonary veins.  N Engl J Med. 1998;  339 659-666
  • 11 Li D, Fareh S, Leung T K, Nattel S. Promotion of atrial fibrillation by heart failure in dogs. Atrial remodeling of a different sort.  Circulation. 1999;  100 87-95
  • 12 Goette A, Staack T, Röcken C et al. Increased expression of extracellular signal-regulated kinase and angiotensin-converting enzyme in human atria during atrial fibrillation.  J Am Coll Cardiol. 2000;  35 1669-1677
  • 13 Kawara T, Derksen R, de Groot J R et al. Activation delay after premature stimulation in chronically diseased human myocardium relates to the architecture of interstitial fibrosis.  Circulation. 2001;  104 3069-3075
  • 14 Jahangiri M, Weir G, Mandal K, Savelieva I, Camm J. Current strategies in the management of atrial fibrillation.  Ann Thorac Surg. 2006;  82 357-364
  • 15 Bakir I, Casselmann F P, Brugada P et al. Current strategies in the surgical treatment of atrial fibrillation: review of the literature and Onze Lieve Vrouw Clinic's strategy.  Ann Thorac Surg. 2007;  83 331-340
  • 16 Roy D, Talajic M, Dorian P et al. Amiodarone to prevent recurrence of atrial fibrillation.  N Engl J Med. 2000;  342 913-920
  • 17 Khargi K, Laczkovics A, Haardt H et al. Concomitant anti-arrhythmic procedures to treat permanent atrial fibrillation in CABG and AVR patients are as effective as in mitral valve patients. Presented at the 3rd EACTS/ESTS Joint Meeting, Leipzig, Germany; 15.09.2004
  • 18 Geidel S, Ostermeyer J, Laß M et al. Permanent atrial fibrillation ablation surgery in CABG and aortic valve patients is at least as effective as in mitral valve disease.  Thorac Cardiovasc Surg. 2006;  54 91-95
  • 19 Gillinov A M, Pettersson G, Rice T W. Esophageal injury during radiofrequency ablation for atrial fibrillation.  J Thorac Cardiovasc Surg. 2001;  122 1239-1240
  • 20 Melo J, Berglin E, Sie H et al. Surgery for atrial fibrillation in mitral patients with and without additional procedures. Results at 5 years from an international registry. Presented at the 86th AATS Annual Meeting, Philadelphia, USA; 01.05.2006
  • 21 Geidel S, Ostermeyer J, Lass M et al. Three years experience with monopolar and bipolar radiofrequency ablation surgery in patients with permanent atrial fibrillation.  Eur J Cardiothorac Surg. 2005;  27 243-249
  • 22 Beukema W P, Sie H T, Misier A R, Delnoy P P, Wellens H J, Elvan A. Predictive factors of sustained sinus rhythm and recurrent atrial fibrillation after radiofrequency modified Maze procedure.  Eur J Cardiothorac Surg. 2008;  34 771-775
  • 23 Gaynor S L, Schuessler R B, Bailey M S et al. Surgical treatment of atrial fibrillation: predictors of late recurrence.  J Thorac Cardiovasc Surg. 2005;  129 104-111
  • 24 Ad N, Barnett S, Lefrak E A et al. Impact of follow-up on the success rate of the cryosurgical maze procedure in patients with rheumatic heart disease and enlarged atria.  J Thorac Cardiovasc Surg. 2006;  131 1073-1079
  • 25 Brignole M, Vardas P, Hoffman E et al. Indications for the use of diagnostic implantable and external ECG loop recorders.  Europace. 2009;  11 671-687

1 Presented at the 39th Annual Meeting of the German Society for Thoracic and Cardiovascular Surgery, Stuttgart, February 14–17, 2010 (V 171).

PD Dr. Stephan Geidel

Department of Cardiac Surgery
Asklepios Klinik St. Georg

Lohmuehlenstr. 5

20099 Hamburg

Germany

Phone: +49 40 18 18 85 41 50

Fax: +49 40 18 18 85 41 84

Email: s.geidel@asklepios.com