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Planta Med 2011; 77(6): 631-640
DOI: 10.1055/s-0030-1250405
Tropical Diseases
Reviews
© Georg Thieme Verlag KG Stuttgart · New York

Natural Products Published in 2009 from Plants Traditionally Used to Treat Malaria

Joanne Bero, Joëlle Quetin-Leclercq
  • 1Pharmacognosy Research Group, Louvain Drug Research Institute, Université Catholique de Louvain, Brussels, Belgium
Further Information

Publication History

received June 15, 2010 revised July 29, 2010

accepted Sept. 9, 2010

Publication Date:
19 October 2010 (online)

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Abstract

Malaria is a major parasitic disease and is responsible for almost one million deaths each year in Africa. There is an urgent need to discover new active compounds. Nature and particularly plants are a potential source of new antimalarial drugs since they contain a quantity of metabolites with a great variety of structures and pharmacological activities. This review covers the compounds with antiplasmodial activity isolated from plants which have been published during 2009 organized according to their phytochemical classes. Details are given for substances with IC50 values ≤ 11 µM. Sixty-seven references are identified.

Key words

antiplasmodial activity - plants - malaria - Plasmodium falciparum

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Joanne Bero

Pharmacognosy Research Group
Louvain Drug Research Institute
Université Catholique de Louvain

Avenue E. Mounier 72

1200 Brussels

Belgium

Phone: +32 27 64 72 92

Fax: +32 27 64 72 93

Email: Joanne.bero@uclouvain.be

    www.thieme-connect.de/ejournals/toc/plantamedica