Download PDF
Thorac Cardiovasc Surg 2012; 60(01): 084-086
DOI: 10.1055/s-0030-1250638
Case Report
Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA.

Heart Failure Resulting from Giant Left Atrial Synovial Sarcoma Metastasis

B. Winkler
1   Cardiac Surgery Basel, University Hospital Basel, Heart Surgery Centre Basel-Bern, Basel, Switzerland
,
M. Grapow
1   Cardiac Surgery Basel, University Hospital Basel, Heart Surgery Centre Basel-Bern, Basel, Switzerland
,
M. Seeberger
2   Department of Anaesthesia, University Hospital Basel, Basel, Switzerland
,
P. Matt
1   Cardiac Surgery Basel, University Hospital Basel, Heart Surgery Centre Basel-Bern, Basel, Switzerland
,
W. Aulitzky
3   Department of Haematology and Oncology, Robert Bosch Hospital, Stuttgart, Germany
,
F. Eckstein
1   Cardiac Surgery Basel, University Hospital Basel, Heart Surgery Centre Basel-Bern, Basel, Switzerland
› Author Affiliations
Further Information

Publication History

12 June 2010

15 October 2010

Publication Date:
21 March 2011 (online)

    Permissions and Reprints All articles of this category

Abstract

Synovial sarcoma metastasis affecting the heart and infiltrating the mitral valve is a very rare pathology. We report the case of a 44-year-old male treated with chemotherapy for atypical synovial sarcoma of the oral mucosa who presented to our clinic after cardiac decompensation with a presumptive diagnosis of myxoma of the left atrium. A large necrotic tumour positive for CK 22, EMA, CD 99 and BCL-2 but negative for translocation in COBRA-FISH analysis by break-apart probe could be excised and revealed a very rare subtype of synovial sarcoma metastasis arising from the endocard of the left atrium. The tumour was resected and the mitral valve reconstructed through ring annuloplasty.

Keywords

heart disease - heart valve surgery - cardiomyopathy
 

  • References

  • 1 Kumar S, Chaudhry MA, Khan I, Duthie DJ, Lindsay S, Kaul P. Metastatic left atrial synovial sarcoma mimicking a myxoma. J Thorac Cardiovasc Surg 2004; 128 (5) 756-758
    CrossrefPubMedSearch in Google Scholar
  • 2 Miller DV, Deb A, Edwards WD, Zehr KJ, Oliveira AM. Primary synovial sarcoma of the mitral valve. Cardiovasc Pathol 2005; 14 (6) 331-333
    CrossrefPubMedSearch in Google Scholar
  • 3 Hazelbag HM, Szuhai K, Tanke HJ, Rosenberg C, Hogendoorn PC. Primary synovial sarcoma of the heart: a cytogenetic and molecular genetic analysis combining RT-PCR and COBRA-FISH of a case with a complex karyotype. Mod Pathol 2004; 17 (11) 1434-1439
    CrossrefPubMedSearch in Google Scholar
  • 4 Policarpio-Nicolas ML, Alasadi R, Nayar R, De Frias DV. Synovial sarcoma of the heart: Report of a case with diagnosis by endoscopic ultrasound-guided fine needle aspiration biopsy. Acta Cytol 2006; 50 (6) 683-686
    CrossrefPubMedSearch in Google Scholar