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DOI: 10.1055/s-0030-1250638
Heart Failure Resulting from Giant Left Atrial Synovial Sarcoma Metastasis
Publikationsverlauf
12. Juni 2010
15. Oktober 2010
Publikationsdatum:
21. März 2011 (online)
![](https://www.thieme-connect.de/media/thoracic/201201/lookinside/thumbnails/10.1055-s-0030-1250638-1.jpg)
Abstract
Synovial sarcoma metastasis affecting the heart and infiltrating the mitral valve is a very rare pathology. We report the case of a 44-year-old male treated with chemotherapy for atypical synovial sarcoma of the oral mucosa who presented to our clinic after cardiac decompensation with a presumptive diagnosis of myxoma of the left atrium. A large necrotic tumour positive for CK 22, EMA, CD 99 and BCL-2 but negative for translocation in COBRA-FISH analysis by break-apart probe could be excised and revealed a very rare subtype of synovial sarcoma metastasis arising from the endocard of the left atrium. The tumour was resected and the mitral valve reconstructed through ring annuloplasty.
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References
- 1 Kumar S, Chaudhry MA, Khan I, Duthie DJ, Lindsay S, Kaul P. Metastatic left atrial synovial sarcoma mimicking a myxoma. J Thorac Cardiovasc Surg 2004; 128 (5) 756-758
- 2 Miller DV, Deb A, Edwards WD, Zehr KJ, Oliveira AM. Primary synovial sarcoma of the mitral valve. Cardiovasc Pathol 2005; 14 (6) 331-333
- 3 Hazelbag HM, Szuhai K, Tanke HJ, Rosenberg C, Hogendoorn PC. Primary synovial sarcoma of the heart: a cytogenetic and molecular genetic analysis combining RT-PCR and COBRA-FISH of a case with a complex karyotype. Mod Pathol 2004; 17 (11) 1434-1439
- 4 Policarpio-Nicolas ML, Alasadi R, Nayar R, De Frias DV. Synovial sarcoma of the heart: Report of a case with diagnosis by endoscopic ultrasound-guided fine needle aspiration biopsy. Acta Cytol 2006; 50 (6) 683-686