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DOI: 10.1055/s-0030-1250667
© Georg Thieme Verlag KG Stuttgart · New York
Granulation Tissue Formation following Dumon Airway Stenting: The Influence of Stent Diameter
Publikationsverlauf
received Sept. 11, 2010
Publikationsdatum:
08. April 2011 (online)
![](https://www.thieme-connect.de/media/thoracic/201103/lookinside/thumbnails/10.1055-s-0030-1250667-1.jpg)
Abstract
Objectives: The present study aimed to determine whether stent diameter influences granulation tissue formation following stent placement for major airway stenosis. Patients and Methods: Forty-two stent procedures (32 tracheal stents, 3 carinal stents, and 7 bronchial stents) were performed in 40 patients. Seventy-nine stent edge regions (62 tracheal, 17 bronchial stents) were evaluated in this study. Results: Granulation tissue formation was encountered in 11 patients (28.21 %). Of the 34 upper ends of evaluated tracheal stents, granulation tissue formation was observed in 6 (17.65 %), whereas granulation tissue formation was observed in 2 (7.14 %) of the 28 lower ends of tracheal stents evaluated. Of the 17 bronchial stent edge regions, granulation tissue formation occurred in 3 (17.65 %) (p = 0.4352). The rate of granulation tissue formation was higher in those patients with a stent-to-airway diameter ratio of > 90 % (p < 0.0001). Receiver operating characteristic curve analysis further demonstrated that a cut-off stent-to-airway diameter ratio of 90 % was effective in predicting granulation tissue formation (AUC: 0.897, Std. error = 0.036, p < 0.0001, 95 % CI = 0827–0.968, n = 79). Conclusions: A stent-to-airway diameter ratio of 90 % was found to be the critical cut-off point for predicting granulation tissue formation. Therefore, the optimal stent-to-airway diameter ratio should be ascertained before stent placement.
Key words
stents - trachea - bronchial disease (includes injury - stenosis - tumor - etc.)
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Dr. Chien-Ying Liu, MD
Department of Thoracic Medicine
Chang Gung Memorial Hospital
199 Tun-Hwa N. Road
105 Taipei
Taiwan, Province of China
Telefon: +88 6 33 28 12 00 ext 51 08
Fax: +88 6 33 27 24 74
eMail: cyliu01@adm.cgmh.org.tw