Aktueller Stellenwert des endobronchialen Ultraschalls (EBUS)

Lernziele

Der Leser soll einen Überblick über die unterschiedlichen bronchosonografischen Verfahren und ihren indikationsbezogenen Stellenwert erhalten. Der Inhalt dieses Artikels und insbesondere die daran angeschlossenen CME-Fragen haben einen hohen Praxisbezug und berücksichtigen neben dem Untersuchungsvorgang auch die Probengewinnung und -beurteilung.

• 1 Rusch V W, Asamura H, Watanabe H et al. The IASLC lung cancer staging project: a proposal for a new international lymph node map in the forthcoming seventh edition of the TNM classification for lung cancer.  J Thorac Oncol. 2009;  4 568-577
• 2 Goeckenjan G, Sitter H, Thomas M et al. Prävention, Diagnostik, Therapie und Nachsorge des Lungenkarzinoms. Interdisziplinäre S3-Leitlinie der Deutschen Gesellschaft für Pneumologie und Beatmungsmedizin und der Deutschen Krebsgesellschaft.  Pneumologie. 2010;  64 1-164
• 3 Travis W D, Brambilla E, Noguchi M et al. International association for the study of lung cancer/american thoracic society/european respiratory society international multidisciplinary classification of lung adenocarcinoma.  J Thorac Oncol. 2011;  6 244-285
• 4 Wong M K, Wong M P, Lam D C et al. Endobronchial ultrasound for diagnosis of synchronous primary lung cancers.  Lung Cancer. 2009;  63 154-157
• 5 Fujiwara T, Yasufuku K, Nakajima T et al. The utility of sonographic features during endobronchial ultrasound-guided transbronchial needle aspiration for lymph node staging in patients with lung cancer: a standard endobronchial ultrasound image classification system.  Chest. 2010;  138 641-647
• 6 Wang Memoli J S, El-Bayoumi E, Pastis N J et al. Using EBUS Features to Predict Lymph Node Metastasis in Patients with Lung Cancer.  Chest. [epub ahead of print: 2011 June 2]
• 7 Kurimoto N, Murayama M, Yoshioka S, Nishisaka T. Analysis of the internal structure of peripheral pulmonary lesions using endobronchial ultrasonography.  Chest. 2002;  122 1887-1894
• 8 Kurimoto N, Osada H, Miyazawa T et al. Targeting Area in Metastatic Lymph Nodes in Lung Cancer for Endobronchial Ultrasonography-guided Transbronchial Needle Aspiration.  Journal of Bronchology & Interventional Pulmonology. 2008;  15 134-138 110.1097/LBR.1090b1013e31817ec31366
• 9 Lee H S, Lee G K, Lee H S et al. Real-time endobronchial ultrasound-guided transbronchial needle aspiration in mediastinal staging of non-small cell lung cancer: how many aspirations per target lymph node station?.  Chest. 2008;  134 368-374
• 10 Bungay H K, Pal C R, Davies C W et al. An evaluation of computed tomography as an aid to diagnosis in patients undergoing bronchoscopy for suspected bronchial carcinoma.  Clin Radiol. 2000;  55 554-560
• 11 Annema J T, Versteegh M I, Veselic M et al. Endoscopic ultrasound-guided fine-needle aspiration in the diagnosis and staging of lung cancer and its impact on surgical staging.  J Clin Oncol. 2005;  23 8357-8361
• 12 Herth F J, Eberhardt R, Vilmann P et al. Real-time endobronchial ultrasound guided transbronchial needle aspiration for sampling mediastinal lymph nodes.  Thorax. 2006;  61 795-798
• 13 Herth F J, Ernst A, Eberhardt R et al. Endobronchial ultrasound-guided transbronchial needle aspiration of lymph nodes in the radiologically normal mediastinum.  Eur Respir J. 2006;  28 910-914
• 14 Herth F J, Eberhardt R, Krasnik M, Ernst A. Endobronchial ultrasound-guided transbronchial needle aspiration of lymph nodes in the radiologically and positron emission tomography-normal mediastinum in patients with lung cancer.  Chest. 2008;  133 887-891
• 15 Garcia-Olive I, Monso E, Andreo F et al. Endobronchial ultrasound-guided transbronchial needle aspiration for identifying EGFR mutations.  Eur Respir J. 2010;  35 391-395
• 16 Yasufuku K, Nakajima T, Fujiwara T et al. Utility of endobronchial ultrasound-guided transbronchial needle aspiration in the diagnosis of mediastinal masses of unknown etiology.  Ann Thorac Surg. 2011;  91 831-836
• 17 Garwood S, Judson M A, Silvestri G et al. Endobronchial ultrasound for the diagnosis of pulmonary sarcoidosis.  Chest. 2007;  132 1298-1304
• 18 Nakajima T, Yasufuku K, Kurosu K et al. The role of EBUS-TBNA for the diagnosis of sarcoidosis--comparisons with other bronchoscopic diagnostic modalities.  Respir Med. 2009;  103 1796-1800
• 19 Wong M, Yasufuku K, Nakajima T et al. Endobronchial ultrasound: new insight for the diagnosis of sarcoidosis.  Eur Respir J. 2007;  29 1182-1186
• 20 Herth F J, Morgan R K, Eberhardt R, Ernst A. Endobronchial ultrasound-guided miniforceps biopsy in the biopsy of subcarinal masses in patients with low likelihood of non-small cell lung cancer.  Ann Thorac Surg. 2008;  85 1874-1878
• 21 Darwiche K, Theegarten D, Wohlschläger J, Freitag L. Gewinnung einer EBUS-geführten PE mittels einer neu entwickelten Zange.  Pneumologie. 2011;  65 V65
• 22 Kennedy M P, Jimenez C A, Bruzzi J F et al. Endobronchial ultrasound-guided transbronchial needle aspiration in the diagnosis of lymphoma.  Thorax. 2008;  63 360-365
• 23 Steinfort D P, Conron M, Tsui A et al. Endobronchial ultrasound-guided transbronchial needle aspiration for the evaluation of suspected lymphoma.  J Thorac Oncol. 2010;  5 804-809
• 24 Lederle F A, Niewoehner D E. Lung cancer surgery. A critical review of the evidence.  Arch Intern Med. 1994;  154 2397-2400
• 25 Gould M K, Fletcher J, Iannettoni M D et al. Evaluation of patients with pulmonary nodules: when is it lung cancer? ACCP evidence-based clinical practice guidelines (2nd edition).  Chest. 2007;  132 108-130
• 26 Schreiber G, McCrory D C. Performance characteristics of different modalities for diagnosis of suspected lung cancer: summary of published evidence.  Chest. 2003;  123 115-128
• 27 Yamada N, Yamazaki K, Kurimoto N et al. Factors related to diagnostic yield of transbronchial biopsy using endobronchial ultrasonography with a guide sheath in small peripheral pulmonary lesions.  Chest. 2007;  132 603-608
• 28 Eberhardt R, Ernst A, Herth F J. Ultrasound-guided transbronchial biopsy of solitary pulmonary nodules less than 20 mm.  Eur Respir J. 2009;  34 1284-1287
• 29 Asahina H, Yamazaki K, Onodera Y et al. Transbronchial biopsy using endobronchial ultrasonography with a guide sheath and virtual bronchoscopic navigation.  Chest. 2005;  128 1761-1765
• 30 Huang C-T, Ho C-C, Tsai Y-J et al. Factors influencing visibility and diagnostic yield of transbronchial biopsy using endobronchial ultrasound in peripheral pulmonary lesions.  Respirology. 2009;  14 859
• 31 Steinfort D P, Khor Y H, Manser R L, Irving L B. Radial probe endobronchial ultrasound for the diagnosis of peripheral lung cancer: systematic review and meta-analysis.  Eur Respir J. 2011;  37 902-910
• 32 Goeckenjan G, Sitter H, Thomas M et al. Prevention, diagnosis, therapy, and follow-up of lung cancer: interdisciplinary guideline of the German Respiratory Society and the German Cancer Society.  Pneumologie. 2010;  65 39-59
• 33 Skov B G, Baandrup U, Jakobsen G K et al. Cytopathologic diagnoses of fine-needle aspirations from endoscopic ultrasound of the mediastinum: reproducibility of the diagnoses and representativeness of aspirates from lymph nodes.  Cancer. 2007;  111 234-241
• 34 Varela-Lema L, Fernandez-Villar A, Ruano-Ravina A. Effectiveness and safety of endobronchial ultrasound-transbronchial needle aspiration: a systematic review.  Eur Respir J. 2009;  33 1156-1164