Synthesis 2010(19): 3379-3383  
DOI: 10.1055/s-0030-1257865
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© Georg Thieme Verlag Stuttgart ˙ New York

Synthesis of α-Aminocyclopropylphosphonic Acids

Andrey V. Chemagina, Nikolai V. Yashin*a,b, Yuri K. Grishina, Tamara S. Kuznetsovaa,b, Nikolai S. Zefirova,b
a Lomonosov Moscow State University, Department of Chemistry, Leninskie Gory 1-3, Moscow 119991, Russian Federation
Fax: +7(495)9393969; e-Mail: yashin-n@org.chem.msu.ru;
b IPhAC RAS, Severnyi Proezd 1, Chernogolovka, Moscow Region 142432, Russian Federation
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Publication History

Received 18 May 2010
Publication Date:
22 July 2010 (online)

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Abstract

A convenient, general approach to α-aminocyclopropyl­phosphonic acids via reduction and hydrolysis of α-nitrocyclopropylphosphonates is described. A number of the title compounds were synthesized in excellent yields.

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