Synlett 2010(12): 1878-1879  
DOI: 10.1055/s-0030-1258124
SPOTLIGHT
© Georg Thieme Verlag Stuttgart ˙ New York

Vanadium Oxytrihalide (VOX3)

Thanh-Tuan Bui*
Laboratoire de Chimie de Coordination du CNRS, 205 Route de Narbonne, 31400 Toulouse, France
e-Mail: bui@lcc-toulouse.fr;
Further Information

Publication History

Publication Date:
30 June 2010 (online)

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Introduction

Applications of VOX3 (X = F or Cl) in organic synthesis have gained significant importance in recent years. VOX3 are well-known as strong oxidizing agents promoting both intra- and intermolecular oxidative biaryl coupling. This property has been used for synthesis of natural products, [¹,²] phenanthridine, [³] phenanthrene [4] and phenanthrene-9,10-dione [5] derivatives. It were also used for the synthesis of discotic liquid crystalline triphenylene [6] and heteroanalogues. [7] VOX3 also acted as regio- and stereoselective dimerization agents of stilbene derivatives, [8] and as hydroxylation [9] and aromatization [¹0] agents. Other applications of VOX3 are the synthesis of near-infrared absorbent organic semiconductor vanadyl phthalocyanine for organic electronic applications [¹¹,¹²] and the use as catalysts in asymmetric synthesis. [¹³]