Vanadium Oxytrihalide (VOX₃)

Introduction

Applications of VOX₃ (X = F or Cl) in organic synthesis have gained significant importance in recent years. VOX₃ are well-known as strong oxidizing agents promoting both intra- and intermolecular oxidative biaryl coupling. This property has been used for synthesis of natural products, [¹,²] phenanthridine, [³] phenanthrene [4] and phenanthrene-9,10-dione [5] derivatives. It were also used for the synthesis of discotic liquid crystalline triphenylene [6] and heteroanalogues. [7] VOX₃ also acted as regio- and stereoselective dimerization agents of stilbene derivatives, [8] and as hydroxylation [9] and aromatization [¹0] agents. Other applications of VOX₃ are the synthesis of near-infrared absorbent organic semiconductor vanadyl phthalocyanine for organic electronic applications [¹¹,¹²] and the use as catalysts in asymmetric synthesis. [¹³]

References

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