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Synthesis 2010(21): 3731-3735
DOI: 10.1055/s-0030-1258218
DOI: 10.1055/s-0030-1258218
PAPER
© Georg Thieme Verlag
Stuttgart ˙ New York
Friedel-Crafts Reactions of 2-Naphthol with α-Amido Sulfones and Conversion of the Products with Nucleophiles [¹]
Weitere Informationen
Received
6 July 2010
Publikationsdatum:
18. August 2010 (online)
Publikationsverlauf
Publikationsdatum:
18. August 2010 (online)
![](https://www.thieme-connect.de/media/synthesis/201021/lookinside/thumbnails/10.1055-s-0030-1258218-1.jpg)
Abstract
2-Naphthol underwent Friedel-Crafts reaction with N-benzyloxycarbonylamino sulfones in the presence of InCl3 at room temperature to form the corresponding sulfonyl derivatives in high yields. The products were subsequently reacted with nucleophiles such as allyltributyltin and anisole to replace the sulfonyl group.
Key words
2-naphthol - α-amido sulfone - InCl3 - Friedel-Crafts reaction - nucleophile
Part 209 in the series ‘Studies on Novel Synthetic Methodologies’.
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Part 209 in the series ‘Studies on Novel Synthetic Methodologies’.