Arene and heteroarene carboxylic acids undergo regioselective
arylation and vinylation reactions at the positions ortho (cine)
and ipso to their carboxyl function under
transition-metal catalysis; these reactions are accompanied by carbon-hydrogen
and carbon-carbon bond cleavages, respectively. Recent
progress in this area is summarized in this article.
carboxylic acids - arylation - olefination - C-H bond cleavage - decarboxylation