δ-Hydroxy-α,β-unsaturated aldehydes
undergo smooth coupling with enamines derived from arylamines and
1,3-diketones in the presence of 10% InCl3 in
CH2Cl2 under mild reaction conditions to afford
sugar fused N-aryltetrahydropyridine
derivatives in good yields with high selectivity. The salient features
of this method are high conversions, mild reaction conditions, short
reaction times, high selectivity and operational simplicity.
Perlin aldehyde - 1,3-diketones - indium(III)
salts -
N-aryltetrahydropyridines
