Abstract
Three oxidation procedures were evaluated for the synthesis of
optically pure 2-arylpropionic acids. Efficient, mild, and eco-friendly
conditions were obtained with the system comprising TEMPO, NaClO,
and NaClO2 . Thus a series of profens were
obtained in good to excellent yields.
Key words
oxidation - alcohols - carboxylic acids - anti-inflammatory
agents - profens - TEMPO
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