Synthesis 2010(24): 4261-4267  
DOI: 10.1055/s-0030-1258970
PAPER
© Georg Thieme Verlag Stuttgart ˙ New York

Using Benzotriazole Esters as a Strategy in the Esterification of Tertiary Alcohols

José Antonio Morales-Sernaa, Aline Veraa, Ehecatl Paleoa, Eréndira García-Ríosa, Rubén Gaviñoa, Gustavo García de la Morab, Jorge Cárdenas*a
a Instituto de Química, Universidad Nacional Autónoma de México, Circuito Exterior, Ciudad Universitaria, Coyoacán 04510, D. F. México City, México
Fax: +52(55)56162217; e-Mail: rjcp@unam.mx;
b Departamento de Química Orgánica, Facultad de Química, Universidad Nacional Autónoma de México, Circuito Interior, Ciudad Universitaria, Coyoacán 04510, D. F. México City, México
Further Information

Publication History

Received 13 August 2010
Publication Date:
12 November 2010 (online)

Abstract

Benzotriazole esters formed in situ were found to be efficient intermediates in the esterification of tertiary alcohols using 4-(dimethylamino)pyridine (DMAP) as the base. These mild and basic reaction conditions allow the conversion of various substrates into esters in good yield.