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Synthesis 2011(14): 2303-2309  
DOI: 10.1055/s-0030-1260060
PAPER
© Georg Thieme Verlag Stuttgart ˙ New York

Molybdenum Hexacarbonyl Mediated Alkoxycarbonylation of Aryl Halides

Wei Ren, A. Emi, Motoki Yamane*
Division of Chemistry and Biological Chemistry, School of Physical and Mathematical Sciences, Nanyang Technological University, 21 Nanyang Link, Singapore 637371, Singapore
Fax: +65(6791)1961; e-Mail: yamane@ntu.edu.sg;
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Publikationsverlauf

Received 22 March 2011
Publikationsdatum:
09. Juni 2011 (online)

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Abstract

Mo(CO)6-mediates the alkoxycarbonylation of aryl halides in their reaction with alcohols to afford arenecarboxylic acid esters. The molybdenum carbonyl complexes act as the catalyst and the source with carbon monoxide. The alkoxycarbonylation proceeds with a small excess of carbon monoxide in the form of Mo(CO)6 and the procedure is simple compared to the conventional method, which uses palladium catalyst under gaseous carbon monoxide. Using this procedure, a variety of carboxylic acid esters were prepared.

Key words

molybdenum - carbonyl complexes - carbonylation - esterification - acylation

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8

The additive Et4NCl was sometimes effective in the carbamoylation of aryl halides. See ref. 6.