A Facile Synthesis of α-Fluoro
Ketones Catalyzed by [Cp*IrCl2]2

Nanna Ahlsten; Agnieszka Bartoszewicz; Santosh Agrawal; Belén Martín-Matute

doi:10.1055/s-0030-1260130

SPECIALTOPIC

A Facile Synthesis of α-Fluoro Ketones Catalyzed by [Cp*IrCl₂]₂

Nanna Ahlsten, Agnieszka Bartoszewicz, Santosh Agrawal, Belén Martín-Matute*
Department of Organic Chemistry, The Arrhenius Laboratory, Stockholm University, 106 91 Stockholm, Sweden
Fax: +46(8)154908; e-Mail: belen@organ.su.se;

Abstract

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Abstract

Allylic alcohols are isomerized into enolates (enols) by [Cp*IrCl₂]₂. The enolates react with Selectfluor present in the reaction media. This method produces α-fluoro ketones as single constitutional isomers in high yields.

Key words

iridium - fluorine - isomerization - alcohols - fluoro ketones

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Referenzen

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Zusatzmaterial

Supporting Information

A Facile Synthesis of α-Fluoro Ketones Catalyzed by [Cp*IrCl2]2

A Facile Synthesis of α-Fluoro Ketones Catalyzed by [Cp*IrCl₂]₂