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Synthesis 2011(16): 2595-2599  
DOI: 10.1055/s-0030-1260603
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© Georg Thieme Verlag Stuttgart ˙ New York

Palladium-Catalyzed Domino Heck/C-H Activation/Intermolecular Direct Arylation Reactions

Zhiyao Lu, Yuxin Cui*, Yanxing Jia*
State Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences, Peking University, 38 Xueyuan Road, Beijing 100191, P. R. of China
Fax: +86(10)82805166; e-Mail: yxjia@bjmu.edu.cn;
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Publication History

Received 8 March 2011
Publication Date:
26 May 2011 (online)

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Abstract

A regioselective, palladium-catalyzed domino Heck/C-H activation/intermolecular direct arylation reaction has been developed, providing rapid access to diverse biaryl heterocycles.

Key words

palladium - domino reaction - C-H activation - arylation

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