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DOI: 10.1055/s-0030-1260794
Facile Synthesis of 2,3-Dihydrobenzofuran-3-ylacetic Acids by Novel Electrochemical Sequential Aryl Radical Cyclization-Carboxylation of 2-Allyloxybromobenzenes Using Methyl 4-tert-Butylbenzoate as an Electron-Transfer Mediator
Publication History
Publication Date:
15 June 2011 (online)
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Abstract
Facile synthesis of 2,3-dihydrobenzofuran-3-ylacetic acids and related analogues was successfully carried out by a novel electrochemical aryl radical generation and its 5-exo cyclization followed by a carboxylation sequence of 2-allyloxybromobenzenes by using methyl 4-tert-butylbenzoate as an electron-transfer mediator.
Key words
electrochemical reduction - radical cyclization - fixation of carbon dioxide - radical-anion tandem reaction - 2,3-dihydrobenzofuran-3-ylacetic acids
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- Supporting Information
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References and Notes
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