PSYCH up2date, Table of Contents Psychiatrie und Psychotherapie up2date 2011; 5(3): 133-134DOI: 10.1055/s-0030-1266101 Editorial © Georg Thieme Verlag KG Stuttgart · New York Fett polstert die Nerven Die Rolle von Lipiden in der Ätiopathogenese neuropsychiatrischer Krankheitsbilder Recommend Article Abstract Buy Article All articles of this category Full Text References Literatur 1 Kromhout D. Energy and macronutrient intake in lean and obese middle-aged men (the Zutphen study). Am J Clin Nutr. 1983; 37 295-299 2 Mukamal K J, Rimm E B, Kawachi I et al. Body mass index and risk of suicide among one million US adults. Epidemiology. 2010; 21 82-86 3 Pappolla M A, Bryant-Thomas T K, Herbert D et al. Mild hypercholesterolemia is an early risk factor for the development of Alzheimer amyloid pathology. Neurology. 2003; 61 199-205 4 Féart C, Samieri C, Rondeau V et al. Adherence to a Mediterranean diet, cognitive decline, and risk of dementia. JAMA. 2009; 302 638-648 5 Scarmeas N, Luchsinger J A, Schupf N et al. Physical activity, diet, and risk of Alzheimer disease. JAMA. 2009; 302 627-637 6 Ng T P, Gao Q, Niti M et al. Omega-3 polyunsaturated Fatty Acid supplements and cognitive decline: Singapore longitudinal aging studies. J Nutr Health Aging. 2011; 15 32-35 7 Morris M C, Evans D A, Bienias J L et al. Consumption of fish and n-3 fatty acids and risk of incident Alzheimer disease. Arch Neurol. 2003; 60 940-946 8 Harold D, Abraham R, Hollingworth P et al. Genome-wide association study identifies variants at CLU and PICALM associated with Alzheimer’s disease. Nat Genet. 2009; 41 1088-1093 9 Jones L, Holmans P A, Hamshere M L et al. Genetic evidence implicates the immune system and cholesterol metabolism in the aetiology of Alzheimer’s disease. PLoS One. 2010; 5 e13950 10 Grimm M O, Grimm H S, Patzold A J et al. Regulation of cholesterol and sphingomyelin metabolism by amyloid-beta and presenilin. Nat Cell Biol. 2005; 7 1118-1123 11 Appleton K M, Rogers P J, Ness A R. Updated systematic review and meta-analysis of the effects of n-3 long-chain polyunsaturated fatty acids on depressed mood. Am J Clin Nutr. 2010; 91 757-770 12 Lafourcade M, Larrieu T, Mato S et al. Nutritional omega-3 deficiency abolishes endocannabinoid-mediated neuronal functions. Nat Neurosci. 2011; 14 345-350 13 Darios F, Davletov B. Omega-3 and omega-6 fatty acids stimulate cell membrane expansion by acting on syntaxin 3. Nature. 2006; 440 813-817 14 Kornhuber J, Tripal P, Reichel M et al. Identification of new functional inhibitors of acid sphingomyelinase using a structure-property-activity relation model. J Med Chem. 2008; 51 219-237 15 Kornhuber J, Reichel M, Tripal P et al. The role of ceramide in major depressive disorder. Eur Arch Psychiatry Clin Neurosci. 2009; 259 S199-S204 16 Kornhuber J, Tripal P, Reichel M et al. Functional inhibitors of acid sphingomyelinase (FIASMAs): a novel pharmacological group of drugs with broad clinical applications. Cell Physiol Biochem. 2010; 26 9-20 17 Fuchs B, Schiller J. MALDI-TOF MS analysis of lipids from cells, tissues and body fluids.. In: Quinn P J, Wang X, eds Lipids in Health and Disease.. Berlin: Springer Netherland; 2008: 541-565