Two Pairs of Epimeric Indole Alkaloids from Catharanthus roseus

Abstract

Two pairs of epimeric indole alkaloids (1–4) with a chlorine atom were isolated from the aerial part of Catharanthus roseus. Their structures were established on the basis of the spectroscopic data including UV, IR, HRESIMS, NMR, and X-ray diffraction analyses. The cytotoxic activities of 1–4 against the HepG2 cell line were evaluated.

Key words

Catharanthus roseus - Apocynaceae - indole alkaloid - cytotoxic activity - HepG2 cells

References

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