Planta Med 2011; 77(16): 1818-1821
DOI: 10.1055/s-0030-1271153
Natural Product Chemistry
Original Papers
© Georg Thieme Verlag KG Stuttgart · New York

Two New Ginkgolides from the Leaves of Ginkgo biloba

Hua-Jun Liao1 , Yun-Feng Zheng1 , Hong-Yang Li1 , Guo-Ping Peng1
  • 1College of Pharmacy, Nanjing University of Chinese Medicines, Nanjing, China
Further Information

Publication History

received Nov. 17, 2010 revised May 2, 2011

accepted May 3, 2011

Publication Date:
25 May 2011 (online)

Abstract

Two new diterpenoid compounds, ginkgolide P (1) and ginkgolide Q (2), were isolated from the leaves of Ginkgo biloba L. Their structures were elucidated by various spectroscopic methods, and the structure of 1 was further confirmed by X-ray crystallographic analysis. The activities of the compounds were evaluated against platelet aggregation induced by platelet activating factor (PAF), and the preliminary structure-activity relationship was also discussed.

Supporting Information

References

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Prof. Guo-Ping Peng

College of Pharmacy
Nanjing University of Chinese Medicine

282 Hanzhong Road

Nanjing 210029

P. R. China

Phone: +86 25 86 79 81 86

Fax: +86 25 86 79 81 86

Email: guopingpeng@sohu.com