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DOI: 10.1055/s-0030-1271153
© Georg Thieme Verlag KG Stuttgart · New York
Two New Ginkgolides from the Leaves of Ginkgo biloba
Publikationsverlauf
received Nov. 17, 2010
revised May 2, 2011
accepted May 3, 2011
Publikationsdatum:
25. Mai 2011 (online)
![](https://www.thieme-connect.de/media/plantamedica/201116/lookinside/thumbnails/10.1055-s-0030-1271153-1.jpg)
Abstract
Two new diterpenoid compounds, ginkgolide P (1) and ginkgolide Q (2), were isolated from the leaves of Ginkgo biloba L. Their structures were elucidated by various spectroscopic methods, and the structure of 1 was further confirmed by X-ray crystallographic analysis. The activities of the compounds were evaluated against platelet aggregation induced by platelet activating factor (PAF), and the preliminary structure-activity relationship was also discussed.
Key words
Ginkgoaceae - Ginkgo biloba L. - ginkgolide P - ginkgolide Q - platelet activating factor
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Prof. Guo-Ping Peng
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