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Clin Colon Rectal Surg 2011; 24(1): 054-063
DOI: 10.1055/s-0031-1272824
© Thieme Medical Publishers

Neoplasms of Anal Canal and Perianal Skin

Daniel Leonard1 , David Beddy1 , Eric J. Dozois1
  • 1Division of Colon and Rectal Surgery, Mayo Clinic, Rochester, Minnesota
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Publication History

Publication Date:
23 February 2011 (online)

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ABSTRACT

Tumors of the anus and perianal skin are rare. Their presentation can vary and often mimics common benign anal pathology, thereby delaying diagnosis and appropriate and timely treatment. The anatomy of this region is complex because it represents the progressive transition from the digestive system to the skin with many different co-existing types of cells and tissues. Squamous cell carcinoma of the anal canal is the most frequent tumor found in the anal and perianal region. Less-frequent lesions include Bowen's and Paget's disease, basal cell carcinoma, melanoma, and adenocarcinoma. This article aims to review the clinical presentation, diagnostic evaluation, and treatment options for neoplasms of the anal canal and perianal skin.

KEYWORDS

Anal squamous-cell carcinoma - anal basal-cell carcinoma - anal melanoma - anal Paget's disease - anal Bowen's disease - anal adenocarcinoma

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Eric J DozoisM.D. 

Division of Colon and Rectal Surgery, Mayo Clinic, Gonda 9 South

200 First St. SW, Rochester, MN 55905

Email: Dozois.eric@mayo.edu