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Semin Respir Crit Care Med 2011; 32(1): 069-077
DOI: 10.1055/s-0031-1272871
© Thieme Medical Publishers

Surgical Management of Lung Cancer

Sandra C. Tomaszek1 , Dennis A. Wigle1
  • 1Division of General Thoracic Surgery, Mayo Clinic, Rochester, Minnesota
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Publikationsverlauf

Publikationsdatum:
15. April 2011 (online)

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ABSTRACT

Lung cancer continues to be the most frequent cancer-related cause of death in the United States and throughout the world. Surgical resection is currently the most effective treatment in early-stage non-small-cell lung cancer, and historically the only treatment approach achieving significant cure rates. In advanced disease, therapeutic approaches involving chemotherapy and/or radiation therapy are utilized to improve prognosis, either as part of a neoadjuvant treatment approach followed by surgical resection or as definitive treatment alone. The role of surgery in locally advanced or metastatic non-small-cell lung cancer remains controversial, with more studies required to further refine the application of modern surgical techniques. For any treatment approach, thorough preoperative staging as well as careful patient selection are essential to assess the benefits and risks involved for the patient. Surgical management of early-stage non-small-cell lung cancer and its role in more advanced disease are discussed in this review.

KEYWORDS

Lung cancer - treatment - surgery

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Dennis A WigleM.D. Ph.D. 

Division of General Thoracic Surgery, Mayo Clinic

200 First St. SW, Rochester, MN 55905

eMail: wigle.dennis@mayo.edu