Dtsch Med Wochenschr 2011; 136(15): 769-774
DOI: 10.1055/s-0031-1275805
Aktuelle Diagnostik & Therapie | Review article
Intensivmedizin
© Georg Thieme Verlag KG Stuttgart · New York

Critical-illness-Polyneuropathie und -Myopathie

Critical illness polyneuropathy and myopathyW. Müllges1 , G. Stoll1
  • 1Neurologische Klinik, Universitätsklinikum Würzburg
Further Information

Publication History

eingereicht: 17.10.2010

akzeptiert: 13.1.2011

Publication Date:
05 April 2011 (online)

Literatur

  • 1 Bednarik J, Vondracek P, Dusek L. et al . Risk factors for critical illness polyneuromyopathy.  J Neurol. 2005;  252 343-351
  • 2 Bolton C F, Gilbert J J, Hahn A F, Sibbald W F. Polyneuropathy in critically ill patients.  J Neurol Neurosurg Psychiatry. 1984;  47 1223-1231
  • 3 Bolton C F. Sepsis and the systemic inflammatory response syndrome: neuromuscular manifestations.  Crit Care Med. 1996;  24 1408-1416
  • 4 deJonghe B, Sharshar T, Lefaucher J P. et al . Paresis aquired in the intensive care unit: a prospective multicenter study.  JAMA. 2002;  288 2859-2867
  • 5 deLetter M A, Schmitz P I, Visser L H. et al . Risk factors fort he development of polyneuropathy and myopathy in critically ill patients.  Crit Care Med. 2001;  29 2281-2286
  • 6 Druschky A, Herkert M, Radespiel-Troger M. et al . Critical illness-polyneuropathy: clinical findings and cell culture assay of neurotoxicity by a prospective study.  Intensive Care Med. 2001;  27 686-693
  • 7 Esteban A, Frutos F, Tobin M J. et al . A comparison of four methods of weaning patients from mechanical ventilation.  New Engl J Med. 1995;  332 345-50
  • 8 Feasby T, Banwell B, Benstead T. et al . Guidelines on the use of intravenous immune globulin for neurologic conditions.  Transfus Med Rev. 2007;  21 (Suppl 1) S57-S107
  • 9 Garnacho-Montero J, Madrazo-Osuna J, Garcia-Garmendia J L. et al . Critical illness-Polyneuropathy: risk factors and clinical consequences. A cohort study in septic patients.  Intensive Care Med. 2001;  27 1288-1296
  • 10 Garnacho-Montero J, Amaya-Villar R Garcia-Garmendia JL. et al . Effect of critical illness polyneuropathy on the withdrawal from mechanical ventilation and the length of stay of septic patients.  Crit Care Med. 2005;  33 349-354
  • 11 Guaneri B, Bertolini G, Latronico N. Long-term outcome in patients with critical illness myopathy or neuropathy: the Italian multicenter CRIMYNE study.  J Neurol Neurosurg Psychiatry. 2008;  79 838-841
  • 12 Hermanns G, Vanhorebeck I, Derde S, vanden B erghe G. Metabolic aspects of critical illness polyneuromyopathy.  Crit Care Med. 2009;  9 (suppl) S391-397
  • 13 Herridge M S, Cheung A M, Tansey C M. et al . One year outcomes in survivors of the acute respiratory distress syndrome.  Engl J Med. 2003;  348 683-693
  • 14 Heyland D K, Dhaliwal R, Suchner U. et al . Antioxidant nutrients: a systematic review of trace elements and vitamins in the critically ill patient.  Intensive Care Med. 2005;  31 327-337
  • 15 Hund E. Myopathy in critically ill patients.  Crit Care Med. 1999;  27 2544-2547
  • 16 Intiso D, Amoruso L, Zarelli M. et al . Long-term functional outcome and health status of patients with critical illness polyneuromyopathy.  Acta Neurol Scand. 2010; Aug 19 [epub ahead of print]; 
  • 17 Khan J, Harrison T B, Rich M M. et al . Early development of critical illness myopathy and neuropathy in patients with severe sepsis.  Neurology. 2006;  67 1421-1425
  • 18 Latronico N, Fenzi F, Recupero D. et al . Critical illness myopathy and neuropathy.  Lancet. 1996;  347 1579-1582
  • 19 Latronico N. Neuromuscular alterations in the critically ill patient: critical illness myopathy, critical illness neuropathy, or both?.  Intensive Care Med. 2003;  29 1411-13
  • 20 Latronico N, Peli E, Botteri M. Critical illness myopathy and neuropathy.  Curr Opin Crit Care. 2005;  11 126-132
  • 21 Latronico N, Bertolini G, Guarneri B. et al . Simplified electrophysiological evaluation of peripheral nerves in critically ill patients. The CRIMYNE study.  Crit Care. 2007;  11 (1) R11
  • 22 Lefaucheur J P, Nordine P, Rodriguez P. et al . Origin of ICU aquired paresis determined by direct muscle stimulation.  J Neurol Neurosurg Psychiatr. 2006;  77 500-506
  • 23 Levine S, Nguyen T, Taylor N. et al . Rapid disuse atrophy of diaphragm fibers in mechanically ventilated humans.  New Engl J Med. 2008;  358 1327-1335
  • 24 Marik P E, Zaloga G P. Immunonutrition in critically ill patients: a systematic review and analysis of the literature.  Intensive Care Med. 2008;  34 1980-1990
  • 25 Massa R, Carpenter S, Holland P. et al . Loss and renewal of thick myofilaments in glucocorticoid-treated rat soleus after denervation and reinnervation.  Muscle Nerve. 1992;  15 1290-1298
  • 26 Mertens H G. Disseminierte Polyneuropathie nach Koma.  Nervenarzt. 1961;  32 71-79
  • 27 Mohr M, Englisch L, Roth A. et al . Effects of early treatment with immunoglobulin on critical illness polyneuropathy following multiple organ failure and gram-negative sepsis.  Intensive Care Med. 1997;  23 1144-1149
  • 28 Müllges W, Stoll G. Intensivmedizinische Behandlung neuromuskulärer Krankheiten.  Intensivmedizin up-2-date. 2009;  5 209-28
  • 29 Müllges W, Stoll G. Akuttherapie des Guillain-Berré-Syndroms und der myasthenen Krise. Erkrankungen.  Akt Neurol. 2010;  37 474-484
  • 30 Needham D M. Mobilizing patients in the intensive care unit: improving neuromuscular weakness and physical function.  JAMA. 2008;  300 1685-1690
  • 31 Reinhart K, Brunkhorst F M, Bone H G. et al .Prävention, Therapie und Nachsorge der Sepsis. S2k-Leitlinie der Deutschen Sepsis-Gesellschaft und Deutschen Interdisziplinären Vereinigung für Intensiv- und Notfallmedizin. 2010 www.awmf.org
  • 32 Steinberg K P, Hudson L D, Goodman R B. et al . Efficiacy and safety of corticosteroids for persistent acute respiratory distress syndrome.  New Engl J Med. 2006;  354 1671-1684
  • 33 Tennila A, Salmi T, Pettila V. et al . Early signs of critical illness polyneuropathy in ICU patients.  Intensive Care Med. 2000;  26 1360-1363
  • 34 Tjader I, Rooyackers O, Forsberg A M. et al . Effects on skeletal muscle of intravenous glutamine supplementation in ICU patients.  Intensive Care Med. 2004;  30 266-275
  • 35 van den Berghe C, Wouters P, Weekers F. et al . Intensive insulin therapy in the critically ill patients.  New Engl J Med. 2001;  345 1359-1367
  • 36 van den Berghe C, Schoenheyt K, Becx P. et al . Insulin therapy protects the central and peripheral nervous system of intensive care patients.  Neurology. 2005;  64 1348-1353
  • 37 Williams S, Horrocks I, Ouvrier R A. et al . Critical illness polyneuropathy and myopathy in pediatric intensive care: a review.  Pediatric Crit Care Med. 2007;  8 18-22
  • 38 Zifko U A, Zipko H T, Bolton C F. Clinical and electrophysiological findings in critical illness polyneuropathy.  J Neurol Sci. 1998;  159 186-193
  • 39 Zochodne D W, Bolton C F, Wells G A. et al . Critical illness polyneuropathy.  Brain. 1987;  110 619-642

Priv.-Doz. Dr. Wolfgang Müllges

Neurologische Klinik, Universitätsklinikum Würzburg

Josef Schneider Str.11

97080 Würzburg

Phone: 0931/201-23764

Fax: 0931/201-61796

Email: Muellges_w@klinik.uni-wuerzburg.de