Zusammenfassung
Bei Patienten mit Spondyloarthritiden gibt es geschlechtsbezogene Unterschiede in Krankheitsausprägung und Verlauf. Dies hat mögliche Auswirkungen auf Diagnostik und Therapie der Patienten.
Abstract
There are gender-related aspects concerning the severity and the course of the disease in patients with spondyloarthritis. These differences may have an impact on the diagnosis and therapy for these patients.
Schlüsselwörter
Spondyloarthritis - Ankylosierende Spondylitis - Diagnose - Bildgebung - Therapie
Key words
spondyloarthritis - ankylosing spondylitis - diagnosis - radiography - therapy
Literatur
-
1
Rudwaleit M, van der Heijde D, Landewé R. et al .
The Development of Assessment of SpondyloArthritis international Society (ASAS) Classification Criteria for Axial Spondyloarthritis (Part II): Validation and Final Selection.
Ann Rheum Dis.
2009;
68
777-783
-
2
Rudwaleit M van, der Heijde D, Landewè R. et al .
The development of Assessment of SpondyloArthritis International Society classification criteria for peripheral spondyloarthritis and spondyloarthritis in general.
Ann Rheum Dis.
2011;
70
25-31
-
3
Braun J, Sieper J.
Ankylosing spondylitis.
Lancet.
2007;
369
1379-1390
-
4
Polley HF, Slocumb CH.
Rheumatoid Spondylitis: a study of 1 035 cases.
Ann Arch Intern Med.
1947;
26
240-249
-
5
Kennedy LG, Will R, Calin A.
Sex ratio in the spondyloarthropathies and its relationship to phenotypic expression, mode of inheritance and age at onset.
J Rheumatol.
1993;
20
1900-1904
-
6
Deutsches Rheuma-Forschungszentrum Berlin. Ausgewählte Aspekte der Erwachsenen Kerndokumentation .
http://dgrh.de/fileadmin/media/Forschung/Versorgungsforschung/ErwachsenenKerndok/standardpraesentation_kerndoku_dgrh_website_07_04_2009.pdf
online geprüft am 14.01.2011
-
7
Calin A, Brophy S, Blake D.
Impact of sex on inheritance of ankylosing spondylitis: a cohort study.
Lancet.
1999;
354
1687-1690
-
8
Miceli-Richard C, Said-Nahal R, Breban M.
Impact of sex on inheritance of ankylosing Spondylitis [letter].
Lancet.
2000;
355
1097-1098
-
9
Brophy S, Taylor G, Blake D. et al .
The Interrelationship Between Sex, Susceptibility Factors, and Outcome in Ankylosing Spondylitis and Its Associated Disorders Including Inflammatory Bowel Disease, Psoriasis, and Iritis.
J Rheumatol.
2003;
30
2054-2058
-
10
Straub RH, Struharova S, Schölmerich J. et al .
No alterations of serum levels of adrenal and gonadal hormones in patients with ankylosing spondylitis.
Clin Exp Rheumatol.
2002;
20
(S 28)
S52-S59
-
11
Gooren LJ, Giltay EJ, van Schaardenburg D. et al .
Gonadal and adrenal sex steroids in ankylosing Spondylitis.
Rheum Dis Clin North Am.
2000;
26
968-987
-
12
Jiminez-Balderas FJ, Tapia-Serrano R, Madero-Cervera JI. et al .
Ovarian function studies in active ankylosing spondylitis in women. Clinical response to estrogen therapy.
J Rheumatol.
1990;
17
497-502
-
13
Averns HL, Oxtoby J, Taylor HG. et al .
Smoking and outcome in ankylosing spondylitis.
Scand J Rheumatol.
1996;
25
138-142
-
14
Ward MM.
Predictors of the Progression of Functional Disability in Patients with Ankylosing Spondylitis.
J Rheumatol.
2002;
29
1420-1425
-
15
Lee W, Reveille JD, Davis Jr JC. et al .
Are there gender differences in the severity of ankylosing spondylitis? Results from the PSOAS cohort.
Ann Rheum Dis.
2007;
66
633-638
-
16
Feldtkeller E, Khan MA, van der Linden S. et al .
Age at disease onset and diagnosis delay in HLA-B27 negative vs.
positive patients with ankylosing spondylitis
Rheumatol.
2003;
23
61-66
-
17
Van der Linden SM, Valkenburg HA, de Jongh BM. et al .
The risk of developing ankylosing spondylitis in HLA B 27 positive individuals. A comparison of relatives of spondylitis patients with the general population.
Arthritis Rheum.
1984;
27
241-249
-
18
Rudwaleit M, Haibel H, Baraliakos X. et al .
The Early Disease Stage in Axial Spondyloarthritis.
Arthritis Rheum.
2009;
60
717-727
-
19
Sampaio-Barros PD, Conde RA, Donadi EA. et al .
Undifferentiated Spondyloarthropathies in Brazilians: Importance of HLA-B27 and the B7-CREG Alleles in Characterization and Disease Progression.
J Rheumatol.
2003;
30
2632-2637
-
20
Rojas-Vargas M, Munoz-Gomaris E, Escudero A. et al .
First signs and symptoms of Spondyloarthritis – data from an inception cohort with a disease course of two years or less (REGISPONDER-Early).
Rheumatol.
2009;
48
404-409
-
21
Roussou E, Sultana S.
Spondyloarthritis in women: differences in disease onset, clinical presentation, and Bath Ankylosing Spondylitis Disease Activity and Functional indices (BASDAI and BASFI) between men and women with spondyloarthritides.
Clin Rheumatol.
2011;
30
121-127
-
22
Gensler LS, Ward MM, Reveille JD. et al .
Clinical, radiographic and functional differences between juvenile-onset and adult-onset ankylosing spondylitis: results from the PSOAS cohort.
Ann Rheum Dis.
2008;
67
232-237
-
23
O’Shea FD, Boyle E, Riarh R. et al .
Comparison of clinical and radiographic severity of juvenile-onset versus adult-onset ankylosing spondylitis.
Ann Rheum Dis.
2009;
68
1407-1412
-
24
Stone M, Warren RW, Bruckel J. et al .
Juvenile-Onset Ankylosing Spondylitis Is Associated With Worse Functional Outcomes Than Adult-Onset Ankylosing Spondylitis.
Arthritis Rheum.
2005;
53
445-451
-
25
Van der Weijden MA, van Denderen JC, Lems JC. et al .
Low bone mineral density is related to male gender and decreased functional capacity in early spondyloarthropathies.
Clin Rheumatol.
2010;
Aug 10 [Epub ahead of print]
-
26
Dagfinrud H, Mengshoel AM, Hagen KB. et al .
Health status of patients with ankylosing spondylitis: a comparison with the general population.
Ann Rheum Dis.
2004;
63
1605-1610
-
27
Martindale J, Smith J, Sutton C. et al .
Disease and psychological status in ankylosing spondylitis.
Rheumatol.
2006;
45
1288-1293
-
28
Ward MM.
Health-Related Quality of Life in Ankylosing Spondylitis: A Survey of 175 Patients.
Arthritis Care Res.
1999;
12
147-155
-
29
Zink A, Mau W, Schneider M.
Epidemiologische und sozialmedizinische Aspekte entzündlich-rheumatischer Systemerkrankungen.
Internist.
2001;
42
211-222
-
30
Østensen M, Fuhrer L, Mathieu R. et al .
A prospective study of pregnant patients with rheumatoid arthritis and ankylosing spondylitis using validated clinical instruments.
Ann Rheum Dis.
2004;
63
1212-1217
-
31
Förger F, Villiger PM, Østensen M.
Pregnancy in Patients With Ankylosing Spondylitis: Do Regulatory T Cells Play a Role?.
Arthritis Rheum.
2009;
61
279-283
-
32
Boonen A, vander Cruyssen B, de Vlam K. et al .
Spinal Radiographic Changes in Ankylosing Spondylitis: Association with Clinical Characteristics and Functional Outcome.
J Rheumatol.
2009;
36
1249-1255
-
33
Doran M, Brophy S, Mackay K. et al .
Predictors of Longterm Outcome in Ankylosing Spondylitis.
J Rheumatol.
2003;
30
316-320
-
34
Zochling J, van der Heijde D, Burgos-Vargas R. et al .
ASAS/EULAR recommendations for the management of ankylosing spondylitis.
Ann Rheum Dis.
2006;
65
442-452
-
35
Huscher D, Merksdal K, Thiele K. et al .
Cost of illness in rheumatoid arthritis, ankylosing spondylitis, psoriatic arthritis and systemic lupus erythematosus in Germany.
Ann Rheum Dis.
2006;
65
1175-1183
-
36
Lord PAC, Farragher TM, Lunt M. et al .
Predictors of response to anti-TNF therapy in ankylosing Spondylitis: results from the British Society for Rheumatology Biologics Register.
Rheumatol.
2010;
49
563-570
-
37
Kristensen LE, Karlsson JA, Englund M. et al .
Presence of peripheral arthritis and male sex predicting continuation of anti-tumor necrosis factor therapy in ankylosing Spondylitis: an observational prospective cohort study from South Swedish Arthritis Treatment Group Register.
Arthritis Care Res.
2010;
10
1362-1369
-
38
Fischer-Betz RE, Schneider M.
Biologika in Schwangerschaft und Stillzeit.
Z Rheumatol.
2009;
69
780-787
-
39
Villinger PM, Caliezi G, Cottin V. et al .
Effects of TNF antagonists on sperm characteristics in patients with Spondyloarthritis.
Ann Rheum Dis.
2010;
69
1842-1844
-
40
Boonen A, Brinkhuizen T, Landewé R. et al .
Impact of ankylosing Spondylitis on sick leave, presenteeism and unpaid productivity, and estimation of the societal cost.
Ann Rheum Dis.
2010;
69
1123-1128
-
41
Zink A, Braun J, Listing J. et al .
Disability and Handicap in Rheumatoid Arthritis and Ankylosing Spondylitis – Results from the German Rheumatological Database.
J Rheumatol.
2000;
613-622
-
42
Boonen A, Chorus A, Miederma H. et al .
Employment, work disability, and work days lost in patients with ankylosing Spondylitis: a cross sectional study of Dutch patients.
Ann Rheum Dis.
2001;
60
353-358
-
43
Mau W, Listing J, Huscher D. et al .
Employment Across Chronic Inflammatory Rheumatic Diseases and Comparison with the General Population.
J Rheumatol.
2005;
32
721-728
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