1College of Pharmacy, Chungnam National University, Daejeon, Republic of Korea
2Diabetic Complications Research Center, Division of Traditional Korean Medicine Integrated Research, Korea Institute of Oriental Medicine, Daejeon, Republic of Korea
3College of Pharmacy, Ewha Womans University, Seoul, Republic of Korea
4College of Pharmacy, Catholic University of Daegu, Gyeongbuk, Republic of Korea
Four new biphenyl and biphenyl ether quinolizidine N-oxide alkaloids, 5-epi-dihydrolyfoline N-oxide (1), decamine N-oxide (2), lagerstroemine N-oxide (3), and lagerine N-oxide (4), were isolated from the aerial parts of Lagerstroemia indica, and their structures were established by extensive spectroscopic studies. In addition, the inhibitory effects of isolated compounds on rat lens aldose reductase (RLAR) were examined.
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