Zusammenfassung
Das perinatale Outcome von anämischen Feten hat sich in den letzten Jahren erheblich
verbessert. Mittels Titerkontrollen, Abschätzen des fetalen Anämiegrads durch Doppler-Sonografie
und Messung der Spitzenflussgeschwindigkeit der A. cerebri media als nicht invasivem
und damit risikolosem Verfahren, sowie der Möglichkeit der intrauterinen Behandlung
durch Nabelschnurbluttransfusion können letale Verläufe heute in den meisten Fällen
vermieden werden. Anämische Feten können so noch vor dem Auftreten eines Hydrops,
was mit einer signifikant schlechteren Prognose vergesellschaftet ist, rechtzeitig
erkannt und im weiteren Schwangerschaftsverlauf engmaschig überwacht und gegebenenfalls
therapiert werden. In dieser Arbeit wird ein Überblick über die Ursachen der fetalen
Anämie, die Diagnostik und Überwachung dieser Risikoschwangerschaft sowie über die
therapeutischen Möglichkeiten und das fetale Outcome gegeben.
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Dr. Norbert Wagner
Universitätsfrauenklinik Essen
Hufelandstr. 55
45147 Essen
eMail: norbert.wagner@uk-essen.de