Subscribe to RSS
DOI: 10.1055/s-0031-1283050
Platelet Gels and Hemostasis in Facial Plastic Surgery
Publication History
Publication Date:
26 July 2011 (online)
![](https://www.thieme-connect.de/media/fps/201104/lookinside/thumbnails/10.1055-s-0031-1283050-1.jpg)
ABSTRACT
Over the last decade, the availability of autologous and homogenous platelet-rich and fibrin-rich gels has increased. Due to their more widespread availability and the potential benefits of improved hemostasis and wound healing, their use during facial plastic and reconstructive surgery procedures has also grown. These gels, when applied topically, attract inflammatory cells and fibroblasts and stimulate collagen deposition. Various studies have investigated the potential surgical applications and benefits of these gels. What follows is an in-depth review of the various fibrin and platelet gels available. Furthermore, it clarifies the current applications and proven benefits in facial plastic surgery.
KEYWORDS
Platelet-rich plasma - fibrin sealant - hemostasis - ecchymosis
REFERENCES
- 1 Egan K K, Kim D W, Toriumi D M. Tissue adhesives. In: Papel I, Frodel J L, Holt G R, et al, eds. Facial Plastic and Reconstructive Surgery. New York: Thieme; 2009: 91-97
- 2 Por Y C, Shi L, Samuel M, Song C, Yeow V KL. Use of tissue sealants in face-lifts: a metaanalysis. Aesthetic Plast Surg. 2009; 33 336-339
- 3 Whitman D H, Berry R L, Green D M. Platelet gel: an autologous alternative to fibrin glue with applications in oral and maxillofacial surgery. J Oral Maxillofac Surg. 1997; 55 1294-1299
- 4 Sclafani A P. Applications of platelet-rich fibrin matrix in facial plastic surgery. Facial Plast Surg. 2009; 25 270-276
- 5 Powell D M, Chang E, Farrior E H. Recovery from deep-plane rhytidectomy following unilateral wound treatment with autologous platelet gel: a pilot study. Arch Facial Plast Surg. 2001; 3 245-250
- 6 Yoo J, Chandarana S, Cosby R. Clinical application of tissue adhesives in soft-tissue surgery of the head and neck. Curr Opin Otolaryngol Head Neck Surg. 2008; 16 312-317
- 7 Lee S, Pham A M, Pryor S G, Tollefson T, Sykes J M. Efficacy of Crosseal fibrin sealant (human) in rhytidectomy. Arch Facial Plast Surg. 2009; 11 29-33
- 8 Oliver D W, Hamilton S A, Figle A A, Wood S H, Lamberty B GA. A prospective, randomized, double-blind trial of the use of fibrin sealant for face lifts. Plast Reconstr Surg. 2001; 108 2101-2105 discussion 2106-2107
- 9 Zoumalan R, Rizk S S. Hematoma rates in drainless deep-plane face-lift surgery with and without the use of fibrin glue. Arch Facial Plast Surg. 2008; 10 103-107
- 10 Marchac D, Sándor G. Face lifts and sprayed fibrin glue: an outcome analysis of 200 patients. BR J Plast Surg. 1994; 47 (5) 306-309
- 11 Grover R, Jones B M, Waterhouse N. The prevention of haematoma following rhytidectomy: a review of 1078 consecutive facelifts. BR J Plast Surg. 201l; 54 (6) 481-486
- 12 Jones B M, Grover R, Hamilton S. The efficacy of surgical drainage in cervicofacial rhytidectomy: a prospective, randomized, controlled trail. Plast Reconstr Surg. 2007; 120 (1) 263-270
- 13 Oliver D W, Hamilton S A, Figle A A, Wood S H, Lamberty B G. A prospective, randomized, double-blind trial of the use of fibrin sealant for face lifts. Plast Reconstr Surg. 2001; 108 (7) 2101-2107
- 14 Kamer F M, Nguyen D B. Experience with fibrin glue in rhytidectomy. Plast Reconstr Surg. 2007; 120 (4) 1045-1052
- 15 Grossman J A, Capraro P A, Atagi T. A prospective, randomized, double-blind trial of the use of fibrin sealant for face lifts. Plast Reconstr Surg. 2002; 110 (5) 1371-1372
- 16 Fezza J P, Cartwright M, Mack W, Flaharty P. The use of aerosolized fibrin glue in face-lift surgery. Plast Reconstr Surg. 2002; 110 (2) 658-666
- 17 Marchac D, Greensmith A L. Early postoperative efficacy of fibrin glue in face lifts: a prospective randomized trial. Plast Reconstr Surg. 2005; 115 (3) 911-918
- 18 Pryor S G, Sykes J, Tollefson T T. Efficacy of fibrin sealant (human) (Evicel) in rhinoplasty: a prospective, randomized, single-blind trial of the use of fibrin sealant in lateral osteotomy. Arch Facial Plast Surg. 2008; 10 339-344
- 19 Eby J B, Navarro R A, Dunkelman A et al.. The effect of fibrin sealant on the healing of laser-resurfaced skin. Aesthet Surg J. 2001; 21 509-517
- 20 Sclafani A P. Platelet-rich fibrin matrix for improvement of deep nasolabial folds. J Cosmet Dermatol. 2010; 9 66-71
- 21 Toriumi D M, O'Grady K, Desai D, Bagal A. Use of octyl-2-cyanoacrylate for skin closure in facial plastic surgery. Plast Reconstr Surg. 1998; 102 2209-2219
Keith LadnerM.D.
Facial Plastic and Cosmetic Surgery Center
2908 West Azeele Street, Tampa, FL 33609-3110
Email: keithladner@gmail.com