ABSTRACT
Nasal gliomas are congenital, nonmalignant rests of neuroglial tissue that typically present as a craniofacial mass. The differential diagnosis of such masses includes lesions that often require the involvement of various surgical subspecialties, including otolaryngology, neurosurgery, plastic surgery, and ophthalmology. Early surgical excision of these masses is advised to minimize nasal and craniofacial distortion. Accordingly, early diagnosis and management planning are paramount, and advances in prenatal imaging are creating a new role for obstetricians and radiologists in the initiation of diagnostic and therapeutic interventions. We describe the case history of a young patient found to have a craniofacial mass on routine prenatal ultrasound and subsequently managed with a multidisciplinary team approach.
KEYWORDS
Nasal glioma - craniofacial mass - prenatal imaging
REFERENCES
-
1
Rahbar R, Resto V A, Robson C D et al..
Nasal glioma and encephalocele: diagnosis and management.
Laryngoscope.
2003;
113
(12)
2069-2077
-
2
Riffaud L, Ndikumana R, Azzis O, Cadre B.
Glial heterotopia of the face.
J Pediatr Surg.
2008;
43
(12)
e1-e3
-
3
Niedzielska G, Niedzielski A, Kotowski M.
Nasal ganglioglioma—difficulties in radiological imaging.
Int J Pediatr Otorhinolaryngol.
2008;
72
(2)
285-287
-
4
Hoving E W.
Nasal encephaloceles.
Childs Nerv Syst.
2000;
16
(10-11)
702-706
-
5
Patterson K, Kapur S, Chandra R S.
“Nasal gliomas” and related brain heterotopias: a pathologist's perspective.
Pediatr Pathol.
1986;
5
(3-4)
353-362
-
6
Uemura T, Yoshikawa A, Onizuka T, Hayashi T.
Heterotopic nasopharyngeal brain tissue associated with cleft palate.
Cleft Palate Craniofac J.
1999;
36
(3)
248-251
-
7
Grzegorczyk V, Brasseur-Daudruy M, Labadie G, Cellier C, Verspyck E.
Prenatal diagnosis of a nasal glioma.
Pediatr Radiol.
2010;
40
(10)
1706-1709
-
8
De Biasio P, Scarso E, Prefumo F, Odella C, Rossi A, Venturini P L.
Prenatal diagnosis of a nasal glioma in the mid trimester.
Ultrasound Obstet Gynecol.
2006;
27
(5)
571-573
-
9
Pakkasjärvi N, Salminen P, Kalajoki-Helmiö T, Rintala R, Pitkäranta A.
Respiratory distress secondary to nasopharyngeal glial heterotopia.
Eur J Pediatr Surg.
2008;
18
(2)
117-118
-
10
Husein O F, Collins M, Kang D R.
Neuroglial heterotopia causing neonatal airway obstruction: presentation, management, and literature review.
Eur J Pediatr.
2008;
167
(12)
1351-1355
-
11
Hedlund G.
Congenital frontonasal masses: developmental anatomy, malformations, and MR imaging.
Pediatr Radiol.
2006;
36
(7)
647-662
quiz 726-727
-
12
Morgan D W, Evans J N.
Developmental nasal anomalies.
J Laryngol Otol.
1990;
104
(5)
394-403
-
13
Wu C L, Tsao L Y, Yang A D, Chen M K.
Endoscopic surgery for nasal glioma mimicking encephalocele in infancy.
Skull Base.
2008;
18
(6)
401-404
-
14
Burren K A, Savery D, Massa V et al..
Gene-environment interactions in the causation of neural tube defects: folate deficiency increases susceptibility conferred by loss of PAX3 function.
Hum Mol Genet.
2008;
17
(23)
3675-3685
Harrison W LinM.D.
Massachusetts Eye and Ear Infirmary
243 Charles Street, Boston, MA 02114
Email: harrison_lin@meei.harvard.edu
