DMW - Deutsche Medizinische Wochenschrift, Table of Contents Dtsch Med Wochenschr 2011; 136(39): 1959-1963DOI: 10.1055/s-0031-1286370 Aktuelle Diagnostik & Therapie | Review article Kardiologie © Georg Thieme Verlag KG Stuttgart · New York Diagnostik der Low-Gradient-Aortenklappenstenose Diagnosis of low-gradient aortic valve stenosisS. Fateh-Moghadam1 , M. Steeg1 , W. Bocksch1 1Medizinische Klinik III, Abteilung für Kardiologie und Kreislauferkrankungen, Universitätsklinikum der Eberhard-Karls-Universität Tübingen Recommend Article Abstract Buy Article Schlüsselwörter Doputamin-Stressechokardiographie - Low-Gradient-Aortenklappenstenose - kontraktile Reserve Keywords dobutamine stress echocardiography - low-gradient aortic valve stenosis - contractile reserve Full Text References Literatur 1 Bermejo J, Yotti R. Low-gradient aortic valve stenosis: value and limitations of dobutamine stress testing. Heart. 2007; 93 298-302 2 Bonow R O, Carabello B A, Kanu C. et al . ACC/AHA 2006 guidelines for the management of patients with valvular heart disease: a report of the American College of Cardiology/American Heart Task Force on Practice Guidelines (writing committee to revise the 1998 Guidelines for the management of patients with valvular heart disease):developed in collaboration with the Society of Cardiovascular Anesthesiologists: endorsed by the Society for Cardiovascular Angiography and Interventions and the Society of thoracic Surgeons. Circulation. 2006; 114 e84-e2231 3 Burwash I G, Thomas D D, Sadahiro M. et al . Dependence of Gorlin formula and continuity equation valve areas on transvalvular volume flow rate in valvular aortic stenosis. Circulation. 1994; 89 827-835 4 Chambers J. Low „gradient”. Low flow aortic stenosis. Heart. 2006; 92 554-558 5 Connolly H M, Oh J K, Schaff H V. et al . Severe aortic stenosis with low transvalvular gradient and severe left ventricular dysfunction: result of aortic valve replacement in 52 patients. Circulation. 2000; 101 1940-1946 6 Higgins J R, Arimie R, Currier J. Low-gradient aortic stenosis. Assessment, treatment and outcome. Catheter Cardiovasc Interv. 2008; 72 731-738 7 Flachskampf F A. Physikalische und technische Grundlagen. In: Flachskampf, Ed Praxis der Echokardiographie, Das Referenzwerk zur echokardiographischen Diagnostik. Stuttgart, New York: Georg Thieme Verlag; 2007 8 Grayburn P A. Assessment of low-gradient aortic stenosis with dobutamine. Circulation. 2006; 113 604-606 9 Kadem L, Rieu R, Dumesnil J G. et al . Flow-dependent changes in Doppler derived aortic valve effective orifice area are real and not due to artefacts. J Am Coll Cardiol. 2006; 47 131-137 10 Monin J L, Quéré J P, Monchi M. et al . Low-gradient aortic stenosis. Operative risk stratification and predictors for long-term outcome: a multicenter study using dobutamine stress hemodynamics. Circulation. 2003; 108 319-324 11 Monin J, Monchi M, Gest V. et al . Aortic stenosis with severe left ventricular dysfunction and low transvalvular pressure gradients. Risk stratification by low-dose dobutamine echocardiography. J Am Coll Cardiol. 2001; 37 21101-21107 12 Nishimura R A, Grantham A, Connolly H M. et al . Low-output, low-gradient aortic stenosis in patients with depressed left ventricular systolic function. The clinical utility of the dobutamine challenge in the catheterization laboratory. Circulation. 2002; 106 809-813 13 Schillern N B, Shah P M, Crawford M. et al . Recommendation for quantitation of the left ventricle by two-dimensional echocardiography: American Society of Echocardiography Committee on Standards. Subcommittee on Quantitation of Two-Dimensional Echocardiograms. J Am Soc Echocardiography. 1989; 2 358-367 14 Skjaerpe T, Hegrenaes L, Hatle L. Noninvasive estimation of valve area in patients with aortic stenosis by Doppler ultrasound and two dimensional echocardiography. Circulation. 1985; 72 810-818 PD Dr. med. Suzanne Fateh-Moghadam MD Medizinische Klinik IIIKardiologie und KreislauferkrankungenUniversitätsklinikum der Eberhard-Karls-Universität Tübingen Otfried-Müller-Straße 10 72076 Tübingen Phone: 07071/2983688 Fax: 07071/295749 Email: suzanne.fateh-moghadam@med.uni-tuebingen.de