Organ Failure: Central Nervous System

Neeraj Naval; Satish Chandolu; Marek Mirski

doi:10.1055/s-0031-1287867

Seminars in Respiratory and Critical Care Medicine, Table of Contents

Semin Respir Crit Care Med 2011; 32(5): 587-597
DOI: 10.1055/s-0031-1287867

Organ Failure: Central Nervous System

Neeraj Naval¹ , Satish Chandolu¹ , Marek Mirski¹

¹Neurosciences: Department of Anesthesiology/Critical Care Medicine, Neurology, Neurosurgery, Johns Hopkins University School of Medicine, Baltimore, Maryland

Abstract

ABSTRACT

Central nervous system (CNS) failure represents a spectrum of disease ranging from mild neurological impairment that may have motor, sensory, visual, speech, cognitive manifestations, or a combination thereof, to comatose states and brain death. This article summarizes the common causes of CNS failure and analyzes the role of clinical, radiological, laboratory, and other ancillary testing in establishing the underlying diagnosis and assessing severity of CNS failure in each condition; we also comment on various treatment options for each of the causes of CNS failure.

KEYWORDS

Central nervous system failure - subarachnoid hemorrhage - intracerebral hemorrhage - ischemic stroke - traumatic brain injury - anoxic brain injury - status epilepticus - encephalopathy

Full Text

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Marek MirskiM.D. Ph.D.

Neurosciences: Department of Anesthesiology/Critical Care Medicine, Neurology, Neurosurgery; Johns Hopkins University School of Medicine

600 N. Wolfe St., Meyer 8-140, Baltimore, MD 21287

Email: mmirski@jhmi.edu