A Stereodivergent Route to Four
Stereoisomeric 3′-Acetoxycyclopentenylglycine Derivatives

Indranil Kundu; Ratnava Maitra; Manoranjan Jana; Shital K Chattopadhyay

doi:10.1055/s-0031-1289645

PAPER

A Stereodivergent Route to Four Stereoisomeric 3′-Acetoxycyclopentenylglycine Derivatives

Indranil Kundu, Ratnava Maitra, Manoranjan Jana, Shital K Chattopadhyay*
Department of Chemistry, University of Kalyani, Kalyani 741235, West Bengal, India
Fax: +91(33)25828282; e-Mail: skchatto@yahoo.com;

Abstract

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Abstract

A short and efficient synthetic route to four stereoisomeric 3′-acetoxycyclopentenylglycine derivatives from l-serine has been developed. The method features a stereoselective conjugate addition and ring-closing metathesis as key steps.

Key words

amino acids - chiral pool - metathesis - Michael addition - stereoselective synthesis

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