A Facile Multicomponent Reaction
Involving Isoquinoline, Dimethyl Allenedicarboxylate,
and 2-Oxo-1H-indol-3-ylidenes

Rejithamol Rajan; Beneesh Pattoorpadi Babu; Amit Kumar; Rony Rajan Paul; C. R. Sinu; Eringathodi Suresh; Vijay Nair

doi:10.1055/s-0031-1289666

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A Facile Multicomponent Reaction Involving Isoquinoline, Dimethyl Allenedicarboxylate, and 2-Oxo-1H-indol-3-ylidenes

Rejithamol Rajan^a, Beneesh Pattoorpadi Babu^a, Amit Kumar^a, Rony Rajan Paul^a, C. R. Sinu^a, Eringathodi Suresh^b, Vijay Nair*^a
^a Organic Chemistry Section, National Institute for Interdisciplinary Science and Technology (CSIR), Trivandrum 695 019, India
Fax: +91(471)2491712; e-Mail: vijaynair_2001@yahoo.com;
^b Analytical Science Division, Central Salt and Marine Research Institute, Bhavanagar 364 002, India

Abstract

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Abstract

Transient zwitterions generated from dimethyl allenedicarboxylate and isoquinoline were successfully intercepted with 2-oxo-1H-indol-3-ylidenes to result in a facile multicomponent reaction under mild conditions.

Key words

zwitterions - allenes - multicomponent reactions - indoles - isoquinoline

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