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Exp Clin Endocrinol Diabetes 2012; 120(04): 234-237
DOI: 10.1055/s-0031-1291344
Article
© J. A. Barth Verlag in Georg Thieme Verlag KG Stuttgart · New York

Medullary Thyroid Nodules by Measurement of Calcitonin (Ct) in Aspiration Needle Washout in Patients with Multinodular Goiter and Moderately Elevated Serum Ct

Autor*innen

  • P. Trimboli

    1   Section of Endocrinology and Diabetology, Ospedale Israelitico, Rome, Italy

  • G. Nigri

    2   Sapienza University 2nd School of Medicine ,Ospedale S. Andrea, Rome, Italy

  • F. Romanelli

    3   Department of Experimental Medicine, Sapienza University, Rome, Italy

  • D. D. Cicciarella Modica

    4   Section of Pathology, Ospedale Israelitico, Rome, Italy

  • A. Crescenzi

    4   Section of Pathology, Ospedale Israelitico, Rome, Italy

  • S. Valabrega

    2   Sapienza University 2nd School of Medicine ,Ospedale S. Andrea, Rome, Italy

  • L. Giovanella

    5   Department of Nuclear Medicine and Thyroid Centre, Oncology Institute of Southern Switzerland, Bellinzona, Switzerland
Weitere Informationen

Publikationsverlauf

received 15. Juli 2011
first decision 15. Juli 2011

accepted 18. Oktober 2011

Publikationsdatum:
10. Februar 2012 (online)

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Abstract

The accuracy of fine needle aspiration cytology (FNAC) is low in medullary thyroid carcinomas (MTC). Recently, a few papers analyzed the measurement of calcitonin (Ct) in washout of the needle after aspiration (WO-Ct) suggesting that this approach may be useful in patients with high serum Ct.

Here we reported, for the first time in our best knowledge, 3 patients with multinodular goiter, moderately elevated serum Ct, high value of WO-Ct, and medullary outcome. These findings suggest that in presence of high serum Ct, FNAC should be performed in all nodules, and it should be combined with WO-Ct in all cases.

Key words

medullary thyroid carcinoma - calcitonin - washout measurement - fine needle aspiration
 

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