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DOI: 10.1055/s-0031-1291423
Usefulness of colonoscopic examination with indigo carmine in diagnosing microscopic colitis
Publikationsverlauf
submitted: 17. Februar 2011
accepted after revision: 11. Juli 2011
Publikationsdatum:
04. November 2011 (online)
![](https://www.thieme-connect.de/media/endoscopy/201112/lookinside/thumbnails/10.1055-s-0031-1291423-1.jpg)
Microscopic colitis, comprising collagenous colitis and lymphocytic colitis, is epitomized by chronic watery diarrhea, endoscopically normal colonic mucosa, and characteristic histopathological features. Reports on chromoendoscopic findings in microscopic colitis are scarce and in this paper we describe such findings. We have examined 13 patients with microscopic colitis by means of chromoendoscopy with indigo carmine 0.2 % – 0.5 %. In all 13 cases continuous mucosal changes were seen, with disappearance of innominate grooves or with irregularity of grooves. The segmental distribution of abnormal chromoendoscopic findings corresponded almost completely with the microscopic features. A diffuse mosaic pattern was found in five of 10 cases of collagenous colitis and in all three cases of lymphocytic colitis. Uneven surface was seen in four cases of collagenous colitis, one of collagenous colitis in remission, and one of lymphocytic colitis, and a nodular surface was recorded in five cases of collagenous colitis but in none of the lymphocytic colitis cases. If these findings can be reproduced in larger series of microscopic colitis cases, the need for biopsies as a diagnostic tool might be restricted to patients where chromoendoscopy shows clear mucosal changes, thereby saving costs and limiting possible complications associated with multiple biopsies.
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References
- 1 Pardi DS, Loftus jr EV, Smyrk TC et al. The epidemiology of microscopic colitis: a population based study in Olmsted County, Minnesota. Gut 2007; 56: 504-508
- 2 Olesen M, Eriksson S, Bohr J et al. Microscopic colitis: a common diarrhoeal disease. An epidemiological study in Orebro, Sweden, 1993-1998. Gut 2004; 53: 346-350
- 3 Sato S, Benoni C, Tóth E et al. Chromoendoscopic appearance of collagenous colitis – a case report using indigo carmine. Endoscopy 1998; 30: S80-81
- 4 Sato S, Matsui T, Tsuda S et al. Endoscopic abnormalities in a Japanese patient with collagenous colitis. J Gastroenterol 2003; 38: 812-813
- 5 Tada M, Katoh S, Kohli Y et al. On the dye spraying method in colonofiberscopy. Endoscopy 1977; 8: 70-74
- 6 Thijs WJ, van Baarlen J, Kleibeuker JH et al. Microscopic colitis: prevalence and distribution throughout the colon in patients with chronic diarrhoea. Neth J Med 2005; 63: 137-140
- 7 Offner FA, Jao RV, Lewin KJ et al. Collagenous colitis: a study of the distribution of morphological abnormalities and their histological detection. Hum Pathol 1999; 30: 451-457
- 8 Cimmino DG, Mella JM, Pereyra L et al. A colorectal mosaic pattern might be an endoscopic feature of collagenous colitis. J Crohns Colitis 2010; 4: 139-143