Learning, techniques, and complications of endoscopic ultrasound (EUS)-guided sampling in gastroenterology: European Society of Gastrointestinal Endoscopy (ESGE) Technical Guideline

M. Polkowski; A. Larghi; B. Weynand; C. Boustière; M. Giovannini; B. Pujol; J.-M. Dumonceau

doi:10.1055/s-0031-1291543

Endoscopy, Table of Contents

Endoscopy 2012; 44(02): 190-206
DOI: 10.1055/s-0031-1291543

Guideline

Learning, techniques, and complications of endoscopic ultrasound (EUS)-guided sampling in gastroenterology: European Society of Gastrointestinal Endoscopy (ESGE) Technical Guideline

M. Polkowski

¹Department of Gastroenterology and Hepatology, Medical Centre for Postgraduate Education and Department of Gastroenterology, The M. Sklodowska-Curie Memorial Cancer Center and Institute of Oncology, Warsaw, Poland

,

A. Larghi

²Digestive Endoscopy Unit, Universita’ Cattolica del Sacro Cuore, Rome, Italy

,

B. Weynand

³CHU Mont-Godinne, Université catholique de Louvain, Yvoir, Belgium

,

C. Boustière

⁴Department of Digestive Endoscopy, Hôpital Saint Joseph, Marseille, France

,

M. Giovannini

⁵Endoscopic Unit, Paoli-Calmettes Institut, Marseille, France

,

B. Pujol

⁶Department of Gastroenterology, Hôpital Privé Jean Mermoz, Lyon, France

,

J.-M. Dumonceau

⁷Service of Gastroenterology and Hepatology, Geneva University Hospitals, Geneva, Switzerland

› Author Affiliations

Abstract

This article is the second of a two-part publication that expresses the current view of the European Society of Gastrointestinal Endoscopy (ESGE) about endoscopic ultrasound (EUS)-guided sampling, including EUS-guided fine needle aspiration (EUS-FNA) and EUS-guided Trucut biopsy. The first part (the Clinical Guideline) focused on the results obtained with EUS-guided sampling, and the role of this technique in patient management, and made recommendations on circumstances that warrant its use. The current Technical Guideline discusses issues related to learning, techniques, and complications of EUS-guided sampling, and to processing of specimens. Technical issues related to maximizing the diagnostic yield (e. g., rapid on-site cytopathological evaluation, needle diameter, microcore isolation for histopathological examination, and adequate number of needle passes) are discussed and recommendations are made for various settings, including solid and cystic pancreatic lesions, submucosal tumors, and lymph nodes. The target readership for the Clinical Guideline mostly includes gastroenterologists, oncologists, internists, and surgeons while the Technical Guideline should be most useful to endoscopists who perform EUS-guided sampling. A two-page executive summary of evidence statements and recommendations is provided.

Full Text

References

References
1 Dumonceau JM, Polkowski M, Larghi A et al. Indications, results and clinical impact of endoscopic ultrasound (EUS)-guided sampling in gastroenterology: European Society of Gastrointestinal Endoscopy (ESGE) Clinical Guideline. Endoscopy 2011; 43: 897-912
2 Dumonceau JM, Riphaus A, Aparicio JR et al. European Society of Gastrointestinal Endoscopy, European Society of Gastroenterology and Endoscopy Nurses and Associates, and the European Society of Anaesthesiology Guideline: Non-anesthesiologist administration of propofol for GI endoscopy. Endoscopy 2010; 42: 960-974
3 Dumonceau JM, Andriulli A, Deviere J et al. European Society of Gastrointestinal Endoscopy (ESGE) Guideline: prophylaxis of post-ERCP pancreatitis. Endoscopy 2010; 42: 503-515
4 Harbour R, Miller J. A new system for grading recommendations in evidence based guidelines. BMJ 2001; 323: 334-336
5 Chang KJ. EUS-guided FNA: the training is moving. Gastrointest Endosc 2004; 59: 69-73
6 Barthet M, Gasmi M, Boustière C et al. EUS training in a live pig model: does it improve echo endoscope hands-on and trainee competence?. Endoscopy 2007; 39: 535-539
7 Rösch T. State of the art lecture: endoscopic ultrasonography: training and competence. Endoscopy 2006; 38: 69-72
8 Savides TJ, Fisher AH, Gress FG et al. 1999 ASGE endoscopic ultrasound survey. Gastrointest Endosc 2000; 52: 745-750
9 Wasan SM, Kapadia AS, Adler DG. EUS training and practice patterns among gastroenterologists completing training since 1993. Gastrointest Endosc 2005; 62: 914-920
10 Ho KY. Survey of endoscopic ultrasonographic practice and training in the Asia-Pacific region. J Gastroenterol Hepatol 2006; 21: 1231-1235
11 Das A, Mourad W, Lightdale CJ et al. An international survey of the clinical practice of EUS. Gastrointest Endosc 2004; 60: 765-770
12 Maffei M, Dumortier J, Dumonceau JM. Self-training in unsedated transnasal EGD by endoscopists competent in standard peroral EGD: prospective assessment of the learning curve. Gastrointest Endosc 2008; 67: 410-418
13 Eloubeidi MA, Tamhane A. EUS-guided FNA of solid pancreatic masses: a learning curve with 300 consecutive procedures. Gastrointest Endosc 2005; 61: 700-708
14 Mertz H, Gautam S. The learning curve for EUS-guided FNA of pancreatic cancer. Gastrointest Endosc 2004; 59: 33-37
15 Harewood GC, Wiersema LM, Halling AC et al. Influence of EUS training and pathology interpretation on accuracy of EUS-guided fine needle aspiration of pancreatic masses. Gastrointest Endosc 2002; 55: 669-673
16 Eisen GM, Dominitz JA, Faigel DO et al. Guidelines for credentialing and granting privileges for endoscopic ultrasound. Gastrointest Endosc 2001; 54: 811-814
17 Sorbi D, Vazquez-Sequeiros E, Wiersema MJ. A simple phantom for learning EUS-guided FNA. Gastrointest Endosc 2003; 57: 580-583
18 Matsuda K, Tajiri H, Hawes RH. How shall we experience EUS and EUS-FNA before the first procedure? The development of learning tools. . Dig Endosc 2004; 16: 236-239
19 Bussen D, Sailer M, Fuchs KH et al. A teaching model for endorectal ultrasound-guided biopsy and drainage of pararectal tumors. Endoscopy 2004; 36: 217-219
20 Bhutani MS, Aveyard M, Stills HF. Improved model for teaching interventional EUS. Gastrointest Endosc 2000; 52: 400-403
21 Klapman JB, Logrono R, Dye CE et al. Clinical impact of on-site cytopathology interpretation on endoscopic ultrasound-guided fine needle aspiration. Am J Gastroenterol 2003; 98: 1289-1294
22 LeBlanc JK, Emerson RE, Dewitt J et al. A prospective study comparing rapid assessment of smears and ThinPrep for endoscopic ultrasound-guided fine-needle aspirates. Endoscopy 2010; 42: 389-394
23 Sarker SK, Albrani T, Zaman A et al. Procedural performance in gastrointestinal endoscopy: live and simulated. World J Surg 2010; 34: 1764-1770
24 Vilmann P, Saftoiu A. Endoscopic ultrasound-guided fine needle aspiration biopsy: equipment and technique. J Gastroenterol Hepatol 2006; 21: 1646-1655
25 Wiersema MJ, Levy MJ, Harewood GC et al. Initial experience with EUS-guided trucut needle biopsies of perigastric organs. Gastrointest Endosc 2002; 56: 275-278
26 Varadarajulu S, Fraig M, Schmulewitz N et al. Comparison of EUS-guided 19-gauge Trucut needle biopsy with EUS-guided fine-needle aspiration. Endoscopy 2004; 36: 397-401
27 Siddiqui UD, Rossi F, Rosenthal LS et al. EUS-guided FNA of solid pancreatic masses: a prospective, randomized trial comparing 22-gauge and 25-gauge needles. Gastrointest Endosc 2009; 70: 1093-1097
28 Song TJ, Kim JH, Lee SS et al. The prospective randomized, controlled trial of endoscopic ultrasound-guided fine-needle aspiration using 22G and 19G aspiration needles for solid pancreatic or peripancreatic masses. Am J Gastroenterol 2010; 105: 1739-1745
29 Sakamoto H, Kitano M, Komaki T et al. Prospective comparative study of the EUS guided 25-gauge FNA needle with the 19-gauge Trucut needle and 22-gauge FNA needle in patients with solid pancreatic masses. J Gastroenterol Hepatol 2009; 24: 384-390
30 Yusuf TE, Ho S, Pavey DA et al. Retrospective analysis of the utility of endoscopic ultrasound-guided fine-needle aspiration (EUS-FNA) in pancreatic masses, using a 22-gauge or 25-gauge needle system: a multicenter experience. Endoscopy 2009; 41: 445-448
31 Itoi T, Itokawa F, Kurihara T et al. Experimental endoscopy: objective evaluation of EUS needles. Gastrointest Endosc 2009; 69: 509-516
32 Bhutani MS, Suryaprasad S, Moezzi J et al. Improved technique for performing endoscopic ultrasound guided fine needle aspiration of lymph nodes. Endoscopy 1999; 31: 550-553
33 Wallace MB, Kennedy T, Durkalski V et al. Randomized controlled trial of EUS-guided fine needle aspiration techniques for the detection of malignant lymphadenopathy. Gastrointest Endosc 2001; 54: 441-447
34 Puri R, Vilmann P, Săftoiu A et al. Randomized controlled trial of endoscopic ultrasound-guided fine-needle sampling with or without suction for better cytological diagnosis. Scand J Gastroenterol 2009; 44: 499-504
35 Larghi A, Noffsinger A, Dye C et al. EUS-guided fine needle tissue acquisition by using high negative pressure suction for the evaluation of solid masses: a pilot study. Gastrointest Endosc 2005; 62: 768-774
36 Rastogi A, Wani S, Gupta N et al. A prospective, single-blind, randomized, controlled trial of EUS-guided FNA with and without a stylet. Gastrointest Endosc 2011; 74: 58-64
37 Wani S, Gupta N, Gaddam S et al. A comparative study of endoscopic ultrasound guided fine needle aspiration with and without a stylet. Dig Dis Sci 2011; 56: 2409-2414
38 Sahai AV, Paquin SC, Gariépy G. A prospective comparison of endoscopic ultrasound-guided fine needle aspiration results obtained in the same lesion, with and without the needle stylet. Endoscopy 2010; 42: 900-903
39 Dumonceau JM. Should we discard the needle stylet during EUS-FNA?. Endoscopy 2011; 43: 167
40 Napoleon B, Alvarez-Sanchez MV, Gincoul R et al. Contrast-enhanced harmonic endoscopic ultrasound in solid lesions of the pancreas: results of a pilot study. Endoscopy 2010; 42: 564-570
41 Giovannini M, Thomas B, Erwan B et al. Endoscopic ultrasound elastography for evaluation of lymph nodes and pancreatic masses: a multicenter study. World J Gastroenterol 2009; 15: 1587-1593
42 Rogart JN, Loren DE, Singu BS et al. Cyst wall puncture and aspiration during EUS-guided fine needle aspiration may increase the diagnostic yield of mucinous cysts of the pancreas. J Clin Gastroenterol 2011; 45: 164-169
43 Al-Haddad M, Gill KR, Raimondo M et al. Safety and efficacy of cytology brushings versus standard fine-needle aspiration in evaluating cystic pancreatic lesions: a controlled study. Endoscopy 2010; 42: 127-132
44 Thomas T, Bebb J, Mannath J et al. EUS-guided pancreatic cyst brushing: a comparative study in a tertiary referral centre. JOP 2010; 11: 163-169
45 Sendino O, Fernández-Esparrach G, Solé M et al. Endoscopic ultrasonography-guided brushing increases cellular diagnosis of pancreatic cysts: A prospective study. Dig Liver Dis 2010; 42: 877-881
46 Al-Haddad M, Raimondo M, Woodward T et al. Safety and efficacy of cytology brushings versus standard FNA in evaluating cystic lesions of the pancreas: a pilot study. Gastrointest Endosc 2007; 65: 894-898
47 Nguyen YP, Maple JT, Zhang Q et al. Reliability of gross visual assessment of specimen adequacy during EUS-guided FNA of pancreatic masses. Gastrointest Endosc 2009; 69: 1264-1270
48 Kocjan G, Chandra A, Cross P et al. BSCC Code of Practice – fine needle aspiration cytology. Cytopathology 2009; 20: 283-296
49 Nasuti JF, Gupta PK, Baloch ZW. Diagnostic value and cost-effectiveness of on-site evaluation of fine-needle aspiration specimens: review of 5,688 cases. Diagn Cytopathol 2002; 27: 1-4
50 Woon C, Bardales RH, Stanley MW et al. Rapid assessment of fine needle aspiration and the final diagnosis – how often and why the diagnoses are changed. Cytojournal 2006; 3: 25
51 Chang KJ, Katz KD, Durbin TE et al. Endoscopic ultrasound-guided fine-needle aspiration. Gastrointest Endosc 1994; 40: 694-699
52 Erickson RA, Sayage-Rabie L, Beissner RS. Factors predicting the number of EUS-guided fine-needle passes for diagnosis of pancreatic malignancies. Gastrointest Endosc 2000; 51: 184-190
53 Savides TJ, Donohue M, Hunt G et al. EUS-guided FNA diagnostic yield of malignancy in solid pancreatic masses: a benchmark for quality performance measurement. Gastrointest Endosc 2007; 66: 277-282
54 Eloubeidi MA, Jhala D, Chhieng DC et al. Yield of endoscopic ultrasound-guided fine-needle aspiration biopsy in patients with suspected pancreatic carcinoma. Cancer 2003; 99: 285-292
55 Gress FG, Hawes RH, Savides TJ et al. Endoscopic ultrasound-guided fine-needle aspiration biopsy using linear array and radial scanning endosonography. Gastrointest Endosc 1997; 45: 243-250
56 Jhala NC, Jhala D, Eltoum I et al. Endoscopic ultrasound-guided fine-needle aspiration biopsy: a powerful tool to obtain samples from small lesions. Cancer 2004; 102: 239-246
57 Williams DB, Sahai AV, Aabakken L et al. Endoscopic ultrasound guided fine needle aspiration biopsy: a large single centre experience. Gut 1999; 44: 720-726
58 Eloubeidi MA, Tamhane A, Jhala N et al. Agreement between rapid onsite and final cytologic interpretations of EUS-guided FNA specimens: implications for the endosonographer and patient management. Am J Gastroenterol 2006; 101: 2841-2847
59 Wiersema MJ, Vilmann P, Giovannini M et al. Endosonography-guided fine-needle aspiration biopsy: diagnostic accuracy and complication assessment. Gastroenterology 1997; 112: 1087-1095
60 Cleveland P, Gill KRS, Coe SG et al. An evaluation of risk factors for inadequate cytology in EUS-guided FNA of pancreatic tumors and lymph nodes. Gastrointest Endosc 2010; 71: 1194-1199
61 Iglesias-Garcia J, Dominguez-Munoz JE, Abdulkader I et al. Influence of on-site cytopathology evaluation on the diagnostic accuracy of endoscopic ultrasound-guided fine needle aspiration (EUS-FNA) of solid pancreatic masses. Am J Gastroenterol 2011; 106: 1705-1710
62 Cherian PT, Mohan P, Douiri A et al. Role of endoscopic ultrasound-guided fine-needle aspiration in the diagnosis of solid pancreatic and peripancreatic lesions: is onsite cytopathology necessary?. HPB (Oxford) 2010; 12: 389-395
63 Moller K, Papanikolaou IS, Toermer T et al. EUS-guided FNA of solid pancreatic masses: high yield of 2 passes with combined histologic-cytologic analysis. Gastrointest Endosc 2009; 70: 60-69
64 Wittmann J, Kocjan G, Sgouros SN et al. Endoscopic ultrasound-guided tissue sampling by combined fine needle aspiration and trucut needle biopsy: a prospective study. Cytopathology 2006; 17: 27-33
65 Pellisé Urquiza M, Fernández-Esparrach G, Solé M et al. Endoscopic ultrasound-guided fine needle aspiration: predictive factors of accurate diagnosis and cost-minimization analysis of on-site pathologist. Gastroenterol Hepatol 2007; 30: 319-324
66 Layfield LJ, Bentz JS, Gopez EV. Immediate on-site interpretation of fine-needle aspiration smears: a cost and compensation analysis. Cancer 2001; 93: 319-322
67 Savoy AD, Raimondo M, Woodward TA et al. Can endosonographers evaluate on-site cytologic adequacy? A comparison with cytotechnologists. . Gastrointest Endosc 2007; 65: 953-957
68 Hikichi T, Irisawa A, Bhutani MS et al. Endoscopic ultrasound-guided fine-needle aspiration of solid pancreatic masses with rapid on-site cytological evaluation by endosonographers without attendance of cytopathologists. J Gastroenterol 2009; 44: 322-328
69 LeBlanc JK, Ciaccia D, Al-Assi MT et al. Optimal number of EUS-guided fine needle passes needed to obtain a correct diagnosis. Gastrointest Endosc 2004; 59: 475-481
70 Turner BG, Cizginer S, Agarwal D et al. Diagnosis of pancreatic neoplasia with EUS and FNA: a report of accuracy. Gastrointest Endosc 2010; 71: 91-98
71 Hoda KM, Rodriguez SA, Faigel DO. EUS-guided sampling of suspected GI stromal tumors. Gastrointest Endosc 2009; 69: 1218-1223
72 Mekky MA, Yamao K, Sawaki A et al. Diagnostic utility of EUS-guided FNA in patients with gastric submucosal tumors. Gastrointest Endosc 2010; 71: 913-919
73 Nguyen P, Feng JC, Chang KJ. Endoscopic ultrasound (EUS) and EUS-guided fine-needle aspiration (FNA) of liver lesions. Gastrointest Endosc 1999; 50: 357-361
74 Singh P, Mukhopadhyay P, Bhatt B et al. Endoscopic ultrasound versus CT scan for detection of the metastases to the liver: results of a prospective comparative study. J Clin Gastroenterol 2009; 43: 367-373
75 Yoshida S, Yamashita K, Yokozawa M et al. Diagnostic findings of ultrasound-guided fine-needle aspiration cytology for gastrointestinal stromal tumors: proposal of a combined cytology with newly defined features and histology diagnosis. Pathol Int 2009; 59: 712-719
76 Papanikolaou IS, Adler A, Wegener K et al. Prospective pilot evaluation of a new needle prototype for endoscopic ultrasonography-guided fine-needle aspiration: comparison of cytology and histology yield. Eur J Gastroenterol Hepatol 2008; 20: 342-348
77 Iglesias-Garcia J, Dominguez-Munoz E, Lozano-Leon A et al. Impact of endoscopic ultrasound-guided fine needle biopsy for diagnosis of pancreatic masses. World J Gastroenterol 2007; 13: 289-293
78 Yasuda I, Tsurumi H, Omar S et al. Endoscopic ultrasound-guided fine-needle aspiration biopsy for lymphadenopathy of unknown origin. Endoscopy 2006; 38: 919-924
79 Voss M, Hammel P, Molas G et al. Value of endoscopic ultrasound guided fine needle aspiration biopsy in the diagnosis of solid pancreatic masses. Gut 2000; 46: 244-249
80 Ardengh JC, Paulo GA, Nakao FS et al. Endoscopic ultrasound guided fine-needle aspiration core biopsy: comparison between an automatic biopsy device and two conventional needle systems. Acta Gastroenterol Latinoam 2008; 38: 105-115
81 Turhan N, Aydog G, Ozin Y et al. Endoscopic ultrasonography-guided fine-needle aspiration for diagnosing upper gastrointestinal submucosal lesions: A prospective study of 50 cases. Diagn Cytopathol 2011; 39: 808-817
82 Ando N, Goto H, Niwa Y et al. The diagnosis of GI stromal tumors with EUS-guided fine needle aspiration with immunohistochemical analysis. Gastrointest Endosc 2002; 55: 37-43
83 Akahoshi K, Sumida Y, Matsui N et al. Preoperative diagnosis of gastrointestinal stromal tumor by endoscopic ultrasound-guided fine needle aspiration. World J Gastroenterol 2007; 13: 2077-2082
84 Aithal GP, Anagnostopoulos GK, Tam W et al. EUS-guided tissue sampling: comparison of “dual sampling” (Trucut biopsy plus FNA) with “sequential sampling” (Trucut biopsy and then FNA as required). Endoscopy 2007; 39: 725-730
85 Larghi A, Verna EC, Stavropoulos SN et al. EUS-guided trucut needle biopsies in patients with solid pancreatic masses: a prospective study. Gastrointest Endosc 2004; 59: 185-190
86 Saftoiu A, Vilmann P, Guldhammer Skov B et al. Endoscopic ultrasound (EUS)-guided Trucut biopsy adds significant information to EUS-guided fine-needle aspiration in selected patients: a prospective study. Scand J Gastroenterol 2007; 42: 117-125
87 Storch I, Shah M, Thurer R et al. Endoscopic ultrasound-guided fine-needle aspiration and Trucut biopsy in thoracic lesions: when tissue is the issue. Surg Endosc 2008; 22: 86-90
88 Storch I, Jorda M, Thurer R et al. Advantage of EUS Trucut biopsy combined with fine-needle aspiration without immediate on-site cytopathologic examination. Gastrointest Endosc 2006; 64: 505-511
89 Fernández-Esparrach G, Sendino O, Solé M et al. Endoscopic ultrasound-guided fine-needle aspiration and trucut biopsy in the diagnosis of gastric stromal tumors: a randomized crossover study. Endoscopy 2010; 42: 292-299
90 Gerke H, Rizk MK, Vanderheyden AD et al. Randomized study comparing endoscopic ultrasound-guided Trucut biopsy and fine needle aspiration with high suction. Cytopathology 2010; 21: 44-51
91 Gines A, Wiersema MJ, Clain JE et al. Prospective study of a Trucut needle for performing EUS-guided biopsy with EUS-guided FNA rescue. Gastrointest Endosc 2005; 62: 597-601
92 Thomas T, Kaye PV, Ragunath K et al. Endoscopic-ultrasound-guided mural trucut biopsy in the investigation of unexplained thickening of esophagogastric wall. Endoscopy 2009; 41: 335-339
93 Thomas T, Kaye PV, Ragunath K et al. Efficacy, safety, and predictive factors for a positive yield of EUS-guided Trucut biopsy: a large tertiary referral center experience. Am J Gastroenterol 2009; 104: 584-591
94 Kipp BR, Pereira TC, Souza PC et al. Comparison of EUS-guided FNA and Trucut biopsy for diagnosing and staging abdominal and mediastinal neoplasms. Diagnostic cytopathology 2009; 37: 549-556
95 Shah SM, Ribeiro A, Levi J et al. EUS-guided fine needle aspiration with and without trucut biopsy of pancreatic masses. JOP 2008; 9: 422-430
96 Dewitt J, McGreevy K, Leblanc J et al. EUS-guided Trucut biopsy of suspected nonfocal chronic pancreatitis. Gastrointest Endosc 2005; 62: 76-84
97 Gleeson FC, Clayton AC, Zhang L et al. Adequacy of endoscopic ultrasound core needle biopsy specimen of nonmalignant hepatic parenchymal disease. Clin Gastroenterol Hepatol 2008; 6: 1437-1440
98 Mizuno N, Bhatia V, Hosoda W et al. Histological diagnosis of autoimmune pancreatitis using EUS-guided trucut biopsy: a comparison study with EUS-FNA. J Gastroenterol 2009; 44: 742-750
99 Song HJ, Park YS, Seo DW et al. Diagnosis of mediastinal tuberculosis by using EUS-guided needle sampling in a geographic region with an intermediate tuberculosis burden. Gastrointest Endosc 2010; 71: 1307-1313
100 Eloubeidi MA, Mehra M, Bean SM. EUS-guided 19-gauge trucut needle biopsy for diagnosis of lymphoma missed by EUS-guided FNA. Gastrointest Endosc 2007; 65: 937-939
101 Iglesias-Garcia J, Poley J-W, Larghi A et al. Feasibility and yield of a new EUS histology needle: results from a multicenter, pooled, cohort study. Gastrointest Endosc 2011; 73: 1189-1196
102 Behling C. A cytology primer for endosonographers. In: Hawes RH, Fockens P, eds. Endosonography. Philadelphia: Saunders Elsevier; 2006: 273-291
103 de Luna R, Eloubeidi MA, Sheffield MV et al. Comparison of ThinPrep and conventional preparations in pancreatic fine-needle aspiration biopsy. Diagn Cytopathol 2004; 30: 71-76
104 Wallace WA, Monaghan HM, Salter DM et al. Endobronchial ultrasound-guided fine-needle aspiration and liquid-based thin-layer cytology. J Clin Pathol 2007; 60: 388-391
105 Arbyn M, Bergeron C, Klinkhamer P et al. Liquid compared with conventional cervical cytology: a systematic review and meta-analysis. Obstet Gynecol 2008; 111: 167-177
106 Fabre M, Ben-Lagha N, Palazzo L. La cytologie en milieu liquide peut-elle remplacer la cytologie conventionnelle pour le diagnostic des ponctions a l’aiguille fine sous échoendoscopie? Résultats d’une étude prospective multicentrique [abstract]. . Gastroenterol Clin Biol 2003; 27: A66
107 Meara RS, Jhala D, Eloubeidi MA et al. Endoscopic ultrasound-guided FNA biopsy of bile duct and gallbladder: analysis of 53 cases. Cytopathology 2006; 17: 42-49
108 Rossi ED, Larghi A, Verna EC et al. Endoscopic ultrasound-guided fine-needle aspiration with liquid-based cytologic preparation in the diagnosis of primary pancreatic lymphoma. Pancreas 2010; 39: 1299-1302
109 Berzosa M, Tsukayama DT, Davies SF et al. Endoscopic ultrasound-guided fine-needle aspiration for the diagnosis of extra-pulmonary tuberculosis. Int J Tuberc Lung Dis 2010; 14: 578-584
110 Michael H, Ho S, Pollack B et al. Diagnosis of intra-abdominal and mediastinal sarcoidosis with EUS-guided FNA. Gastrointest Endosc 2008; 67: 28-34
111 Khashab M, Mokadem M, Dewitt J et al. Endoscopic ultrasound-guided fine-needle aspiration with or without flow cytometry for the diagnosis of primary pancreatic lymphoma – a case series. Endoscopy 2010; 42: 228-231
112 Ribeiro A, Pereira D, Escalón MP et al. EUS-guided biopsy for the diagnosis and classification of lymphoma. Gastrointest Endosc 2010; 71: 851-855
113 Mortensen MB, Fristrup C, Holm FS et al. Prospective evaluation of patient tolerability, satisfaction with patient information, and complications in endoscopic ultrasonography. Endoscopy 2005; 37: 146-153
114 Al-Haddad M, Wallace MB, Woodward TA et al. The safety of fine-needle aspiration guided by endoscopic ultrasound: a prospective study. Endoscopy 2008; 40: 204-208
115 Bournet B, Migueres I, Delacroix M et al. Early morbidity of endoscopic ultrasound: 13 years' experience at a referral center. Endoscopy 2006; 38: 349-354
116 Bentz JS, Kochman ML, Faigel DO et al. Endoscopic ultrasound-guided real-time fine-needle aspiration: clinicopathologic features of 60 patients. Diagn Cytopathol 1998; 18: 98-109
117 Eloubeidi MA, Tamhane A, Varadarajulu S et al. Frequency of major complications after EUS-guided FNA of solid pancreatic masses: a prospective evaluation. Gastrointest Endosc 2006; 63: 622-629
118 Eloubeidi MA, Gress FG, Savides TJ et al. Acute pancreatitis after EUS-guided FNA of solid pancreatic masses: a pooled analysis from EUS centers in the United States. Gastrointest Endosc 2004; 60: 385-389
119 O’Toole D, Palazzo L, Arotçarena R et al. Assessment of complications of EUS-guided fine-needle aspiration. Gastrointest Endosc 2001; 53: 470-474
120 Polkowski M, Gerke W, Jarosz D et al. Diagnostic yield and safety of endoscopic ultrasound-guided trucut biopsy in patients with gastric submucosal tumors: a prospective study. Endoscopy 2009; 41: 329-334
121 Janssen J, König K, Knop-Hammad V et al. Frequency of bacteremia after linear EUS of the upper GI tract with and without FNA. Gastrointest Endosc 2004; 59: 339-344
122 Barawi M, Gottlieb K, Cunha B et al. A prospective evaluation of the incidence of bacteremia associated with EUS-guided fine-needle aspiration. Gastrointest Endosc 2001; 53: 189-192
123 Levy MJ, Norton ID, Clain JE et al. Prospective study of bacteremia and complications with EUS FNA of rectal and perirectal lesions. Clin Gastroenterol Hepatol 2007; 5: 684-689
124 Levy MJ, Norton ID, Wiersema MJ et al. Prospective risk assessment of bacteremia and other infectious complications in patients undergoing EUS-guided FNA. Gastrointest Endosc 2003; 57: 672-678
125 Banerjee S, Shen B, Baron TH et al. Antibiotic prophylaxis for GI endoscopy. Gastrointest Endosc 2008; 67: 791-798
126 Allison MC, Sandoe JAT, Tighe R et al. Antibiotic prophylaxis in gastrointestinal endoscopy. Gut 2009; 58: 869-880
127 Lee LS, Saltzman JR, Bounds BC et al. EUS-guided fine needle aspiration of pancreatic cysts: a retrospective analysis of complications and their predictors. Clin Gastroenterol Hepatol 2005; 3: 231-236
128 Aerts JGJV, Kloover J, Los J et al. EUS-FNA of enlarged necrotic lymph nodes may cause infectious mediastinitis. J Thorac Oncol 2008; 3: 1191-1193
129 Annema JT, Veselic M, Versteegh MI et al. Mediastinitis caused by EUS-FNA of a bronchogenic cyst. Endoscopy 2003; 35: 791-793
130 Jenssen C, Dietrich CF. Endoscopic ultrasound-guided fine-needle aspiration biopsy and trucut biopsy in gastroenterology – An overview. Best Pract Res Clin Gastroenterol 2009; 23: 743-759
131 Erickson RA. EUS-guided FNA. Gastrointest Endosc 2004; 60: 267-279
132 Fazel A, Moezardalan K, Varadarajulu S et al. The utility and the safety of EUS-guided FNA in the evaluation of duplication cysts. Gastrointest Endosc 2005; 62: 575-580
133 Affi A, Vazquez-Sequeiros E, Norton ID et al. Acute extraluminal hemorrhage associated with EUS-guided fine needle aspiration: frequency and clinical significance. Gastrointest Endosc 2001; 53: 221-225
134 Kien-Fong VuC, Chang F, Doig L et al. A prospective control study of the safety and cellular yield of EUS-guided FNA or Trucut biopsy in patients taking aspirin, nonsteroidal anti-inflammatory drugs, or prophylactic low molecular weight heparin. Gastrointest Endosc 2006; 63: 808-813
135 Varadarajulu S, Eloubeidi MA. Frequency and significance of acute intracystic hemorrhage during EUS-FNA of cystic lesions of the pancreas. Gastrointest Endosc 2004; 60: 631-635
136 Brugge WR, Lewandrowski K, Lee-Lewandrowski E et al. Diagnosis of pancreatic cystic neoplasms: a report of the cooperative pancreatic cyst study. Gastroenterology 2004; 126: 1330-1336
137 Chee Y, Crawford J, Watson H et al. Guidelines on the assessment of bleeding risk prior to surgery or invasive procedures. Br J Haematol 2008; 140: 496-504
138 Zuckerman MJ, Hirota WK, Adler DG et al. ASGE guideline: the management of low-molecular-weight heparin and nonaspirin antiplatelet agents for endoscopic procedures. Gastrointest Endosc 2005; 61: 189-194
139 Anderson MA, Ben-Menachem T, Gan SI et al. Management of antithrombotic agents for endoscopic procedures. Gastrointest Endosc 2009; 70: 1060-1070
140 Boustière C, Veitch A, Vanbiervliet G et al. Endoscopy and antiplatelet agents. European Society of Gastrointestinal Endoscopy (ESGE) Guideline. . Endoscopy 2011; 43: 445-461
141 Gress F, Michael H, Gelrud D et al. EUS-guided fine-needle aspiration of the pancreas: evaluation of pancreatitis as a complication. Gastrointest Endosc 2002; 56: 864-867
142 Di Matteo F, Shimpi L, Gabbrielli A et al. Same-day endoscopic retrograde cholangiopancreatography after transduodenal endoscopic ultrasound-guided needle aspiration: do we need to be cautious?. Endoscopy 2006; 38: 1149-1151
143 Hirooka Y, Goto H, Itoh A et al. Case of intraductal papillary mucinous tumor in which endosonography-guided fine-needle aspiration biopsy caused dissemination. J Gastroenterol Hepatol 2003; 18: 1323-1324
144 Paquin SC, Gariépy G, Lepanto L et al. A first report of tumor seeding because of EUS-guided FNA of a pancreatic adenocarcinoma. Gastrointest Endosc 2005; 61: 610-611
145 Eloubeidi MA, Tamhane A, Lopes TL et al. Cervical esophageal perforations at the time of endoscopic ultrasound: a prospective evaluation of frequency, outcomes, and patient management. Am J Gastroenterol 2009; 104: 53-56
146 Doi S, Yasuda I, Iwashita T et al. Needle tract implantation on the esophageal wall after EUS-guided FNA of metastatic mediastinal lymphadenopathy. Gastrointest Endosc 2008; 67: 988-990
147 Shah JN, Fraker D, Guerry D et al. Melanoma seeding of an EUS-guided fine needle track. Gastrointest Endosc 2004; 59: 923-924
148 Micames C, Jowell PS, White R et al. Lower frequency of peritoneal carcinomatosis in patients with pancreatic cancer diagnosed by EUS-guided FNA vs. percutaneous FNA. . Gastrointest Endosc 2003; 58: 690-695

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