Periodontal viruses as a factor in premature birth

The purpose of the study – to examine the significance of viral agents in the periodontal habitat premature birth pregnancy. To do this, examined 30 pregnant women with preterm birth and subsequent development activities in the pregnancy – up to 37 weeks (22–36 weeks). They constituted the group. The control group of 10 women each were mothers with timely deliveries, and pregnant women with clinical signs of threatened abortion at 22–36 weeks duration. All patients conducted virologic investigation of molecular-biological methods (PCR-diagnostics) in real-time thermocycler from Biorad IQ5 using a reagent kit for DNA amplification AmpliSens to identify the most significant viruses. Biological material obtained from the periodontal spaces mother, vagina, cervix, amniotic fluid, placenta, umbilical cord blood newborn.

The research results showed that the fire, the most attractive for viruses in all groups are the periodontal space. But if the virus in the control groups were found in the periodontal space in individual patients, the main group – in 90.0±5.5% (p4 <0.001). In the periodontal spaces were found mainly 2 types of viruses. Of the 27 women in 19 main groups detected Epstein-Barr virus, in 7– parvovirus and one – herpes simplex virus. In all other habitats in almost all cases detected cytomegalovirus. In a study of patients are identified 2 more viruses – adenovirus and influenza A, which we thought had to vegetate in the periodontal space. But in any case, none of the virus was not detected.