ABSTRACT
Thrombosis in children is becoming more prevalent due to increased awareness of these
issues in the pediatric population and advances in medicine. Management of affected
children are challenging due to differences in their hemostatic system compared with
adults. Prospective, controlled trials for management/treatment of children with thrombosis
are lacking. Many of the available guidelines for treatment of thrombosis in children
are extrapolated from adult data and do not account for the uniqueness of the pediatric
hemostatic system, although more research and data are becoming available. This review
will focus on children over 1 year of age, including adolescents, looking at the etiology
of thrombosis, diagnosis, management options, and any associated complications in
this pediatric population.
KEYWORDS
Thrombosis - pediatrics - anticoagulation
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Christine A. MacartneyM.B. D.C.H. M.R.C.P. F.R.C.Path.
Department of Paediatric Haematology, Royal Belfast Hospital for Sick Children, Falls
Road
Belfast BT12 6BE, Northern Ireland, United Kingdom
eMail: christine.macartney@belfasttrust.hscni.net
