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Fortschr Neurol Psychiatr 2012; 80(7): 402-406
DOI: 10.1055/s-0031-1299357
Kasuistik
© Georg Thieme Verlag KG Stuttgart · New York

Primäre amelanotische meningeale Melanomatose

Primary Amelanotic Meningeal Melanomatosis
C. Schulz
1   Abteilung Neurochirurgie, Bundeswehrkrankenhaus Ulm
,
S. Waldeck
2   Abteilung Radiologie, Bundeswehrzentralkrankenhaus Koblenz
› Author Affiliations
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Publication History

Publication Date:
26 March 2012 (online)

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Zusammenfassung

Primäre melanozytäre Läsionen des Zentralnervensystems (ZNS) treten sehr selten auf. Die Ausbreitung von Melanomzellen primär in den Meningen (nicht metastatisch) wird als meningeale Melanomatose bezeichnet. Einige Fallberichte über entweder intrakranielle oder intraspinale primäre meningeale Melanome wurden bereits publiziert. Die amelanotische Variante der primären Melanome des ZNS wird extrem selten beobachtet und bislang sind keine Fälle von primärer amelanotischer meningealer Melanomatose beschrieben worden. Wir präsentieren einen solchen Fall mit kombiniertem Auftreten multipler intrakranieller und intraspinaler Herde.

Abstract

Primary melanocytic lesions of the central nervous system are rare. The spread of melanoma cells primarily into the meningeal layers is referred to as meningeal melanomatosis. A few case reports about either intracranial or intraspinal primary meningeal melanoma were published in the past. The amelanotic variation of primary melanoma in the central nervous system is a very rare event and so far no cases of primary amelanotic meningeal melanomatosis have been described in the current literature. We present a case with combined multiple intracranial and intraspinal primary malignant amelanotic melanomas.

Schlüsselwörter

amelanotisches Melanom - meningeale Melanomatose - primäres ZNS-Melanom

Key words

CNS melanoma - amelanotic melanoma - meningeal melanomatosis
 

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