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Semin intervent Radiol 2012; 29(01): 029-035
DOI: 10.1055/s-0032-1302449
Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA.

Inferior Vena Cava Filters for Primary Prophylaxis: When Are They Indicated?

Eric Wehrenberg-Klee
1   Department of Internal Medicine, Brigham and Women's Hospital, Boston, Massachusetts
,
S. William Stavropoulos
2   Radiology, Division of Interventional Radiology, Hospital of the University of Pennsylvania, Philadelphia, Pennsylvania
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Publikationsdatum:
16. April 2012 (online)

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Abstract

Over the past several years there has been a rapid increase in the number of inferior vena cava (IVC) filters placed for primary thromboprophylaxis. Increased use has occurred in settings where other methods of thromboprophylaxis are viewed to be inadequate, technically challenging, or that place patients at an unacceptably high bleeding risk. These clinical services include trauma, bariatric surgery, neurosurgery, cancer, intensive care unit populations, and patients with a relative contraindication to anticoagulation. We review the studies to date addressing filter placement for these indications. Although preliminary data are promising, the patient populations most likely to benefit from prophylactic IVC filter placement have not been well defined, and randomized studies demonstrating efficacy have not been conducted. Moving forward, it will be critical to accomplish these two tasks if IVC filters are to continue to have a role in primary thromboprophylaxis.

Keywords

ivc filter - thromboprophylaxis - pulmonary embolism prophylaxis
 

  • References

  • 1 Silverstein MD, Heit JA, Mohr DN, Petterson TM, O'Fallon WM, Melton III LJ. Trends in the incidence of deep vein thrombosis and pulmonary embolism: a 25-year population-based study. Arch Intern Med 1998; 158 (6) 585-593
    CrossrefPubMedGoogle Scholar
  • 2 Francis CW. Clinical practice. Prophylaxis for thromboembolism in hospitalized medical patients. N Engl J Med 2007; 356 (14) 1438-1444
    CrossrefPubMedGoogle Scholar
  • 3 Stein PD, Kayali F, Olson RE. Twenty-one-year trends in the use of inferior vena cava filters. Arch Intern Med 2004; 164 (14) 1541-1545
    CrossrefPubMedGoogle Scholar
  • 4 Duszak Jr R, Parker L, Levin DC, Rao VM. Placement and removal of inferior vena cava filters: national trends in the medicare population. J Am Coll Radiol 2011; 8 (7) 483-489
    CrossrefPubMedGoogle Scholar
  • 5 Decousus H, Leizorovicz A, Parent F , et al. A clinical trial of vena caval filters in the prevention of pulmonary embolism in patients with proximal deep-vein thrombosis. Prévention du Risque d'Embolie Pulmonaire par Interruption Cave Study Group. N Engl J Med 1998; 338 (7) 409-415
    CrossrefPubMedGoogle Scholar
  • 6 O'Malley KF, Ross SE. Pulmonary embolism in major trauma patients. J Trauma 1990; 30 (6) 748-750
    CrossrefPubMedGoogle Scholar
  • 7 Geerts WH, Code KI, Jay RM, Chen E, Szalai JP. A prospective study of venous thromboembolism after major trauma. N Engl J Med 1994; 331 (24) 1601-1606
    CrossrefPubMedGoogle Scholar
  • 8 Smoot RL, Koch CA, Heller SF , et al. Inferior vena cava filters in trauma patients: efficacy, morbidity, and retrievability. J Trauma 2010; 68 (4) 899-903
    CrossrefPubMedGoogle Scholar
  • 9 Rosenthal D, Wellons ED, Lai KM, Bikk A, Henderson VJ. Retrievable inferior vena cava filters: initial clinical results. Ann Vasc Surg 2006; 20 (1) 157-165
    CrossrefPubMedGoogle Scholar
  • 10 Allen TL, Carter JL, Morris BJ, Harker CP, Stevens MH. Retrievable vena cava filters in trauma patients for high-risk prophylaxis and prevention of pulmonary embolism. Am J Surg 2005; 189 (6) 656-661
    CrossrefPubMedGoogle Scholar
  • 11 Meier C, Keller IS, Pfiffner R, Labler L, Trentz O, Pfammatter T. Early experience with the retrievable OptEase vena cava filter in high-risk trauma patients. Eur J Vasc Endovasc Surg 2006; 32 (5) 589-595
    CrossrefPubMedGoogle Scholar
  • 12 Johnson III ON, Gillespie DL, Aidinian G, White PW, Adams E, Fox CJ. The use of retrievable inferior vena cava filters in severely injured military trauma patients. J Vasc Surg 2009; 49 (2) 410-416 ; discussion 416
    CrossrefPubMedGoogle Scholar
  • 13 Gonzalez RP, Cohen M, Bosarge P, Ryan J, Rodning C. Prophylactic inferior vena cava filter insertion for trauma: intensive care unit versus operating room. Am Surg 2006; 72 (3) 213-216
    PubMedGoogle Scholar
  • 14 Karmy-Jones R, Jurkovich GJ, Velmahos GC , et al. Practice patterns and outcomes of retrievable vena cava filters in trauma patients: an AAST multicenter study. J Trauma 2007; 62 (1) 17-24 ; discussion 24–25
    CrossrefPubMedGoogle Scholar
  • 15 McMurtry AL, Owings JT, Anderson JT, Battistella FD, Gosselin R. Increased use of prophylactic vena cava filters in trauma patients failed to decrease overall incidence of pulmonary embolism. J Am Coll Surg 1999; 189 (3) 314-320
    CrossrefPubMedGoogle Scholar
  • 16 Rogers FB, Cipolle MD, Velmahos G, Rozycki G, Luchette FA. Practice management guidelines for the prevention of venous thromboembolism in trauma patients: the EAST practice management guidelines work group. J Trauma 2002; 53 (1) 142-164
    CrossrefPubMedGoogle Scholar
  • 17 Antevil JL, Sise MJ, Sack DI , et al. Retrievable vena cava filters for preventing pulmonary embolism in trauma patients: a cautionary tale. J Trauma 2006; 60 (1) 35-40
    CrossrefPubMedGoogle Scholar
  • 18 Cherry RA, Nichols PA, Snavely TM, David MT, Lynch FC. Prophylactic inferior vena cava filters: do they make a difference in trauma patients?. J Trauma 2008; 65 (3) 544-548
    CrossrefPubMedGoogle Scholar
  • 19 Singh P, Lai HM, Lerner RG, Chugh T, Aronow WS. Guidelines and the use of inferior vena cava filters: a review of an institutional experience. J Thromb Haemost 2009; 7 (1) 65-71
    PubMedGoogle Scholar
  • 20 Cuschieri J, Freeman B, O'Keefe G , et al; Inflammation and the Host Response to Injury Collaborative Research Program. Inflammation and the host response to injury a large-scale collaborative project: patient-oriented research core standard operating procedure for clinical care X. Guidelines for venous thromboembolism prophylaxis in the trauma patient. J Trauma 2008; 65 (4) 944-950
    CrossrefPubMedGoogle Scholar
  • 21 Geerts WH, Bergqvist D, Pineo GF , et al; American College of Chest Physicians. Prevention of venous thromboembolism: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines (8th Edition). Chest 2008; 133 (6, Suppl) 381S-453S
    CrossrefPubMedGoogle Scholar
  • 22 Sapala JA, Wood MH, Schuhknecht MP, Sapala MA. Fatal pulmonary embolism after bariatric operations for morbid obesity: a 24-year retrospective analysis. Obes Surg 2003; 13 (6) 819-825
    CrossrefPubMedGoogle Scholar
  • 23 Carmody BJ, Sugerman HJ, Kellum JM , et al. Pulmonary embolism complicating bariatric surgery: detailed analysis of a single institution's 24-year experience. J Am Coll Surg 2006; 203 (6) 831-837
    CrossrefPubMedGoogle Scholar
  • 24 Kaboli P, Henderson MC, White RH. DVT prophylaxis and anticoagulation in the surgical patient. Med Clin North Am 2003; 87 (1) 77-110 , viii
    CrossrefPubMedGoogle Scholar
  • 25 Eriksson S, Backman L, Ljungström KG. The incidence of clinical postoperative thrombosis after gastric surgery for obesity during 16 years. Obes Surg 1997; 7 (4) 332-335 ; discussion 336
    CrossrefPubMedGoogle Scholar
  • 26 Melinek J, Livingston E, Cortina G, Fishbein MC. Autopsy findings following gastric bypass surgery for morbid obesity. Arch Pathol Lab Med 2002; 126 (9) 1091-1095
    PubMedGoogle Scholar
  • 27 Rocha AT, de Vasconcellos AG, da Luz Neto ER, Araújo DM, Alves ES, Lopes AA. Risk of venous thromboembolism and efficacy of thromboprophylaxis in hospitalized obese medical patients and in obese patients undergoing bariatric surgery. Obes Surg 2006; 16 (12) 1645-1655
    CrossrefPubMedGoogle Scholar
  • 28 Frezza EE, Chiriva-Internati M. Venous thromboembolism in morbid obesity and trauma. A review of literature. Minerva Chir 2005; 60 (5) 391-399
    PubMedGoogle Scholar
  • 29 Frezza EE, Wachtel MS. A simple venous thromboembolism prophylaxis protocol for patients undergoing bariatric surgery. Obesity (Silver Spring) 2006; 14 (11) 1961-1965
    CrossrefPubMedGoogle Scholar
  • 30 Gargiulo III NJ, Veith FJ, Lipsitz EC, Suggs WD, Ohki T, Goodman E. Experience with inferior vena cava filter placement in patients undergoing open gastric bypass procedures. J Vasc Surg 2006; 44 (6) 1301-1305
    CrossrefPubMedGoogle Scholar
  • 31 Overby DW, Kohn GP, Cahan MA , et al. Risk-group targeted inferior vena cava filter placement in gastric bypass patients. Obes Surg 2009; 19 (4) 451-455
    CrossrefPubMedGoogle Scholar
  • 32 Birkmeyer NJ, Share D, Baser O , et al; Michigan Bariatric Surgery Collaborative. Preoperative placement of inferior vena cava filters and outcomes after gastric bypass surgery. Ann Surg 2010; 252 (2) 313-318
    CrossrefPubMedGoogle Scholar
  • 33 Winegar DA, Sherif B, Pate V, DeMaria EJ. Venous thromboembolism after bariatric surgery performed by Bariatric Surgery Center of Excellence Participants: analysis of the Bariatric Outcomes Longitudinal Database. Surg Obes Relat Dis 2011; 7 (2) 181-188
    CrossrefPubMedGoogle Scholar
  • 34 ASMBS Position Statement on Prophylactic Measures to Reduce the Risk of Venous Thromboembolism in Bariatric Surgery Patients. http://www.asbs.org/Newsite07/resources/vte_statement.pdt . Accessed July 15, 2011
    PubMedGoogle Scholar
  • 35 Hamilton MG, Hull RD, Pineo GF. Venous thromboembolism in neurosurgery and neurology patients: a review. Neurosurgery 1994; 34 (2) 280-296 ; discussion 296
    CrossrefPubMedGoogle Scholar
  • 36 Dearborn JT, Hu SS, Tribus CB, Bradford DS. Thromboembolic complications after major thoracolumbar spine surgery. Spine 1999; 24 (14) 1471-1476
    CrossrefPubMedGoogle Scholar
  • 37 Dickinson LD, Miller LD, Patel CP, Gupta SK. Enoxaparin increases the incidence of postoperative intracranial hemorrhage when initiated preoperatively for deep venous thrombosis prophylaxis in patients with brain tumors. Neurosurgery 1998; 43 (5) 1074-1081
    CrossrefPubMedGoogle Scholar
  • 38 Fukamachi A, Koizumi H, Nagaseki Y, Nukui H. Postoperative extradural hematomas: computed tomographic survey of 1105 intracranial operations. Neurosurgery 1986; 19 (4) 589-593
    CrossrefPubMedGoogle Scholar
  • 39 Rosner MK, Kuklo TR, Tawk R, Moquin R, Ondra SL. Prophylactic placement of an inferior vena cava filter in high-risk patients undergoing spinal reconstruction. Neurosurg Focus 2004; 17 (4) E6
    CrossrefPubMedGoogle Scholar
  • 40 Leon L, Rodriguez H, Tawk RG, Ondra SL, Labropoulos N, Morasch MD. The prophylactic use of inferior vena cava filters in patients undergoing high-risk spinal surgery. Ann Vasc Surg 2005; 19 (3) 442-447
    CrossrefPubMedGoogle Scholar
  • 41 Ozturk C, Ganiyusufoglu K, Alanay A, Aydogan M, Onat L, Hamzaoglu A. Efficacy of prophylactic placement of inferior vena cava filter in patients undergoing spinal surgery. Spine 2010; 35 (20) 1893-1896
    CrossrefPubMedGoogle Scholar
  • 42 Glotzbecker MP, Bono CM, Harris MB, Brick G, Heary RF, Wood KB. Surgeon practices regarding postoperative thromboembolic prophylaxis after high-risk spinal surgery. Spine 2008; 33 (26) 2915-2921
    CrossrefPubMedGoogle Scholar
  • 43 Khorana AA, Connolly GC. Assessing risk of venous thromboembolism in the patient with cancer. J Clin Oncol 2009; 27 (29) 4839-4847
    CrossrefPubMedGoogle Scholar
  • 44 Blom JW, Doggen CJ, Osanto S, Rosendaal FR. Malignancies, prothrombotic mutations, and the risk of venous thrombosis. JAMA 2005; 293 (6) 715-722
    CrossrefPubMedGoogle Scholar
  • 45 Nalluri SR, Chu D, Keresztes R, Zhu X, Wu S. Risk of venous thromboembolism with the angiogenesis inhibitor bevacizumab in cancer patients: a meta-analysis. JAMA 2008; 300 (19) 2277-2285
    CrossrefPubMedGoogle Scholar
  • 46 Lee AY, Levine MN, Baker RI , et al; Randomized Comparison of Low-Molecular-Weight Heparin versus Oral Anticoagulant Therapy for the Prevention of Recurrent Venous Thromboembolism in Patients with Cancer (CLOT) Investigators. Low-molecular-weight heparin versus a coumarin for the prevention of recurrent venous thromboembolism in patients with cancer. N Engl J Med 2003; 349 (2) 146-153
    CrossrefPubMedGoogle Scholar
  • 47 Prandoni P, Lensing AW, Piccioli A , et al. Recurrent venous thromboembolism and bleeding complications during anticoagulant treatment in patients with cancer and venous thrombosis. Blood 2002; 100 (10) 3484-3488
    CrossrefPubMedGoogle Scholar
  • 48 Damascelli B, Ticha V, Patelli G , et al. Use of a retrievable vena cava filter with low-intensity anticoagulation for prevention of pulmonary embolism in patients with cancer: an observational study in 106 cases. J Vasc Interv Radiol 2011; 22 (9) 1312-1319
    CrossrefPubMedGoogle Scholar
  • 49 Dewdney SB, Benn T, Rimel BJ , et al. Inferior vena cava filter placement in the gynecologic oncology patient: a 15-year institutional experience. Gynecol Oncol 2011; 121 (2) 344-346
    CrossrefPubMedGoogle Scholar
  • 50 Wallace MJ, Jean JL, Gupta S , et al. Use of inferior vena caval filters and survival in patients with malignancy. Cancer 2004; 101 (8) 1902-1907
    CrossrefPubMedGoogle Scholar
  • 51 Athanasoulis CA, Kaufman JA, Halpern EF, Waltman AC, Geller SC, Fan CM. Inferior vena caval filters: review of a 26-year single-center clinical experience. Radiology 2000; 216 (1) 54-66
    CrossrefPubMedGoogle Scholar
  • 52 Jarrett BP, Dougherty MJ, Calligaro KD. Inferior vena cava filters in malignant disease. J Vasc Surg 2002; 36 (4) 704-707
    CrossrefPubMedGoogle Scholar
  • 53 Ghanim AJ, Daskalakis C, Eschelman DJ, Kraft WK. A five-year, retrospective, comparison review of survival in neurosurgical patients diagnosed with venous thromboembolism and treated with either inferior vena cava filters or anticoagulants. J Thromb Thrombolysis 2007; 24 (3) 247-254
    CrossrefPubMedGoogle Scholar
  • 54 Wagman LD, Baird MF, Bennett CL , et al; National Comprehensive Cancer Network. Venous thromboembolic disease. Clinical practice guidelines in oncology. J Natl Compr Canc Netw 2006; 4 (9) 838-869
    PubMedGoogle Scholar
  • 55 Lyman GH, Khorana AA, Falanga A , et al; American Society of Clinical Oncology. American Society of Clinical Oncology guideline: recommendations for venous thromboembolism prophylaxis and treatment in patients with cancer. J Clin Oncol 2007; 25 (34) 5490-5505
    CrossrefPubMedGoogle Scholar
  • 56 Major KM, Bulic S, Rowe VL, Patel K, Weaver FA. Internal jugular, subclavian, and axillary deep venous thrombosis and the risk of pulmonary embolism. Vascular 2008; 16 (2) 73-79
    CrossrefPubMedGoogle Scholar
  • 57 Hirsch DR, Ingenito EP, Goldhaber SZ. Prevalence of deep venous thrombosis among patients in medical intensive care. JAMA 1995; 274 (4) 335-337
    CrossrefPubMedGoogle Scholar
  • 58 Marik PE, Andrews L, Maini B. The incidence of deep venous thrombosis in ICU patients. Chest 1997; 111 (3) 661-664
    CrossrefPubMedGoogle Scholar
  • 59 Wilasrusmee C, Kiranantawat K, Horsirimanont S , et al. Deep venous thrombosis in surgical intensive care unit: prevalence and risk factors. Asian J Surg 2009; 32 (2) 85-88
    CrossrefPubMedGoogle Scholar
  • 60 Murray PT. “Drug dosing in the intensive care unit: the critically ill are a special population too.”. Crit Care Med 2009; 37 (1) 342-343
    CrossrefPubMedGoogle Scholar
  • 61 Zagli G, Tarantini F, Bonizzoli M , et al. Altered pharmacology in the intensive care unit patient. Fundam Clin Pharmacol 2008; 22 (5) 493-501
    CrossrefPubMedGoogle Scholar
  • 62 Priglinger U, Delle Karth G, Geppert A , et al. Prophylactic anticoagulation with enoxaparin: is the subcutaneous route appropriate in the critically ill?. Crit Care Med 2003; 31 (5) 1405-1409
    CrossrefPubMedGoogle Scholar
  • 63 Paton BL, Jacobs DG, Heniford BT, Kercher KW, Zerey M, Sing RF. Nine-year experience with insertion of vena cava filters in the intensive care unit. Am J Surg 2006; 192 (6) 795-800
    CrossrefPubMedGoogle Scholar
  • 64 Greenfield LJ, Proctor MC. Vena caval filter use in patients with sepsis: results in 175 patients. Arch Surg 2003; 138 (11) 1245-1248
    CrossrefPubMedGoogle Scholar
  • 65 Kaufman JA, Kinney TB, Streiff MB , et al. Guidelines for the use of retrievable and convertible vena cava filters: report from the Society of Interventional Radiology multidisciplinary consensus conference. J Vasc Interv Radiol 2006; 17 (3) 449-459
    CrossrefPubMedGoogle Scholar
  • 66 Levy JM, Duszak Jr RL, Akins EW , et al. Inferior vena cava filter placement. American College of Radiology. ACR Appropriateness Criteria. Radiology 2000; 215 (Suppl) 981-997
    PubMedGoogle Scholar
  • 67 Cothren CC, Smith WR, Moore EE, Morgan SJ. Utility of once-daily dose of low-molecular-weight heparin to prevent venous thromboembolism in multisystem trauma patients. World J Surg 2007; 31 (1) 98-104
    CrossrefPubMedGoogle Scholar
  • 68 Scudday T, Brasel K, Webb T , et al. Safety and efficacy of prophylactic anticoagulation in patients with traumatic brain injury. J Am Coll Surg 2011; 213 (1) 148-153 ; discussion 153–154
    CrossrefPubMedGoogle Scholar
  • 69 Koehler DM, Shipman J, Davidson MA, Guillamondegui O. Is early venous thromboembolism prophylaxis safe in trauma patients with intracranial hemorrhage. J Trauma 2011; 70 (2) 324-329
    CrossrefPubMedGoogle Scholar